毛喉鞘蕊花研究进展1.PDFVIP

Scientific Journal of Frontier Chemical Development  December 2012, Volume 2, Issue 4, PP.89‐96  Research Progress on Coleus forskohlii # Hao Cheng, Di Geng, Lianjin Weng, Yuanyuan Han College of Chemical Engineering, Huaqiao University, Xiamen, China #Email: hanyuan@ Abstract Coleus forskohlii (Wild.) Briq. is one of the most important species of the genus Coleus Lour, with a wide variety of traditional medicinal uses in Hindu and Ayurvedic traditional medicine. Coleus forskohlii Wild is the only Plants all known that contains forskolin. Forskolin is the strongest activator of AC that extracted from botanical. It can regulate many kinds of cyto-function in vivo in the way of activating AC directly and raise cAMP of many histiocyte. C. forskohlii will give an increasing impact in application in the future consulting the references about C. forskohlii since 1977, more than 40 terpenoids have been isolated from Coleus forskohlii. Forskolin, the main bioactive composition in this plant, showed activities of lower blood pressure, antidepressiv, antiasthmatic, immunoregulation and so on, chemical and pharmacological researches were summarized, so as to provide scientific basis for the in-depth study and exploitation of C. forskohlii. Key words: Coleus Forskohlii; Forskolin; Chemical Constitution; Terpenoids; Pharmacological Activities 毛喉鞘蕊花的研究进展1 程 浩，耿 頔，翁连进，韩媛媛 华侨大学 化工学院，福建 厦门 361021 摘 要：毛喉鞘蕊花[Coleus forskohlii （Wild.）Briq.] 系唇形科（Labiatae）鞘蕊花属（Coleus Lour）植物，该植物在古印 度被称为“万灵药”，长期用于治疗感冒、咳嗽，心脏病，呼吸紊乱等疾病，我国民间主要用于治疗咳喘、眩晕等病症， 被公认是唯一含有佛司可林的已知植物，佛司可林(forsko1in)为目前所知唯一从