妊娠期高血压重度子痫前期病前预警临床的研究.docVIP

妊娠期高血压重度子痫前期病前预警临床的研究 　　摘要: 目的:探讨妊娠期高血压疾病重度子痫前期孕妇临床病程进展中预警情况。方法:选 择2008年1月至2009年6月,在资源县人民医院妇产科进行早、中、晚期规律产前检查的40例 妊娠 期高血压重度子痫前期患者作为研究组。采用同期正常单胎妊娠80例孕妇作为对照组,记录并分析两组孕妇临床资料。结果:体重指数增长、体重增加、水肿、高血压前期表现 、低蛋白血症、蛋白尿研究组与对照组比较 有极显著性差异(P0.01)。结论:过度体重增加、水肿、高血压前期表现 和低蛋白血症是妊娠期高血压疾病重度子痫前期发生的预警信息。 　　关键词:妊娠期高血压;子痫前期;水肿;高血压;蛋白尿 　　中图分类号: R714.24+5 文献标识码: A 文章编号: 1008-2409(2009)06-1013-03 　　 　　Clinical study of hypertensive disorders of early warning signs in pregnancy severe preeclampsia/HU Mei-xiu,LUO Yan-hong∥The Peoples Hospital of Ziyu an County, Guilin 541400, China 　　Abstract:Objective: To identify the early warning signs of severe preeclampsiaofhypertensive disorders in pregnancy. Methods:A case-control observational study was conducted. 40 pregnant women with severe preeclampsia of hypertensivedisorders in pregnancy, who attended the prenatal clinics of the Peoples Hosp ital of Ziyuan county, from January 2008 to June 2009 were selected as the studygroup,including first trimester, second trimester and third trimester. The control gr oup consisted of 80 healthy pregnant women at the same period.Clinica l data were collected and analyzed. Results: Comparing with the control group, the increase of body mass index;the weight gain;edema;higher percentage of ex perienced pre- hypertension; the low level of plasma albumin;proteinuria in the stud ygroup were significantly higher(P0.01). Conclusions: Excessive weight ga in, edema,pre-hypertension and hypoproteinemia are early warning signs of severe preecla mpsia ofhypertensive disorders in pregnancy. 　　Key words:hypertensive disorders in pregnancy; preeclampsia; edema; hypertens ion; proteinuria 　　 　　妊娠期高血压(Hypertensive disorders in pregnancy)是妊娠期特有的疾病,在我国发病率9.4%～10.4%,该病严重影响母婴健康,是孕产妇和围生儿病率及死亡率的主 要原因 [ 1]。重度子痫前期(preeclampsia)严重威胁孕产妇的生命,但子痫前期的病因 和发病机 制仍不十分清楚,尚无有效的临床预测和预防方法。本研究通过对本院接受规律产前 检查并发生重度子痫前期孕妇的临床资料进行分析,探讨重度子痫前期孕妇临床病程进展中 的预警信息,为进一步提高临床实践中的预警能力和实施重点防范提供依据。 　　 　　1 资料与方法 　　 　　 　　1.1 研究对象 　　选择2008年1月至2009年6月早、中、晚期在资源县人