中国ALK阳性NSCLC诊断专家共识_V1_4讲义教材.pptVIP

中国ALK融合基因阳性非小细胞肺癌诊断共识;中国ALK融合基因阳性非小细胞肺癌诊断共识;ALK+ target population;中国ALK阳性非小细胞肺癌诊断流程图;组织标本类型 手术、活检标本： FFPE标本：推荐FISH、RT-PCR、IHC 新鲜标本：推荐RT-PCR 细胞学标本： 细胞沉渣（pellet）：RT-PCR 细胞蜡块（cell block）：推荐FISH、RT-PCR、IHC ;中国ALK阳性非小细胞肺癌诊断流程图;ALK分离探针FISH原理;FISH诊断;FISH检测的局限性;False positivity vs false negativity ....; ALK FISH interpretaion criteria: 15% split signals, at least 50 tumor cells were analyzed, if the result is equivocal, additional 50 tumor cells should be counted. Positive cells: separated green and orange signals or single red signals identified cells with rearrange