常规吸氧对急性ST段抬高型心肌梗死病人的作用研究-内科学(心血管)专业论文.docxVIP

万方数据 万方数据 目 录 中文摘要 ··········································································································· 1 英文摘要 ··········································································································· 4 英文缩写 ··········································································································· 8 研究论文 常规吸氧对急性 ST 段抬高型心肌梗死病人的作用研究 前言 ··········································································································· 9 材料与方法 ····························································································· 10 结果 ········································································································· 12 附图 ········································································································· 14 附表 ········································································································· 18 讨论 ········································································································· 20 结论 ········································································································· 26 参考文献 ································································································· 27 综述 氧疗在急性心肌梗死患者中的应用 ··················································· 32 致谢 ················································································································· 43 个人简历 ········································································································· 44 中 中 文 摘 要 PAGE 10万方数据 PAGE 10 万方数据 常规吸氧对急性 ST 段抬高型心肌梗死病人的作用研究 摘 要 目的： 急性 ST 段抬高型心肌梗死为在冠状动脉病变基础上，发生冠状动脉 血供急剧减少或中断，使相应的心肌严重而持久地急性缺血导致心肌坏 死。氧气吸入疗法（氧疗）是临床上最常用的抢救及治疗手段之一，自应 用临床至此已有 100 余年历史。且《2015 急性 ST 段抬高型心肌梗死诊断 和治疗指南》指出：所有 STEMI 患者入院后一般处理均应立即给予吸氧 和心电、血压和血氧饱和度监测。然而曾有研究表明给予血氧正常的患者 氧疗可引起冠状动脉血管收缩，血流量下降，氧自由基大量释放等不良反 应，最终导致梗死面积增大。 本实验是一项单中心随机前瞻性临床研究，目的是给予血氧饱和度正 常（指氧监测94%）的 STEMI 患者常规吸氧，与对照组相比是否获益。 方法： 选择 2015 年 1 月至 2015