临床医学毕业论文低分子肝素钙与银杏达莫联用治疗进展性脑梗死疗效观察.docVIP

低分子肝素钙与银杏达莫联用治疗进展性脑梗死疗效观 姓 名： 2014年6月25日 低分子肝素钙与银杏达莫联用治疗进展性脑梗死疗效观察 摘耍】 目的探讨低分子肝素钙与银杏达莫联用治疗进展性脑梗死的 临床疗效。方法将96例进展性脑梗死患者随机分为2组，2组均予常规治疗。 对照组48例予银杏达莫注射液20 mL,每日1次静脉滴注，连续14日；治疗组 48例在对照组基础上联用低分子肝素钙，每次0.5mL，每tl 2次腹壁脐周皮下 注射，连续10日。于治疗前和治疗第3、7、14、28日分别进行神经功能缺损程 度评分，并判定临床疗效。结果治疗组治疗第7、14、28円神经功能缺损评分 明显降低，与治疗前比较差异均有统计学意义(P0.01),与同期对照组比较差异均 有统计学意义(P0.01);对照组第14、28 口祌经功能缺损评分与治疗前比较差异 有统计学意义(P0.01);治疗组显效率、总有效率与对照组比较差异均有统计学意 义((P0.05))，治疗组优于对照组。结论低分子肝素钙与银杏达莫联用治疗进展 性脑梗死可有效终止病情进展，改善神经功能缺损，提高临床疗效。 关键词】脑梗塞肝素低分子量银杏黄酮类双嘧达莫 Clinical observation on therapeutic effect of Low-molecule heparin calcium integrated with Yinxingdamo injection on progressive cerebral infarction Abstract】 Objective To observe the therapeutic effect of low-molecule heparin calcium integrated with Yinxingdamo injection on progressive cerebral infarction. Methods 96 patients with progressive cerebral infarction were randomly divided into two groups. 48 patients in control group，on the basis of routine treatment， were treated by Yinxingdamo injection 20 ml once a day，with a treatment course of 14 days. The other 48 patients in treatment group, on the basis of control group，were treated by low-molecule heparin calcium 0.5 mL once，twice a day，with a treatment course of 10 days. The scoring of nervous function defect before treatment and on the 3rd，7th，14th，28th day after treatment were conducted，and the therapeutic effects were evaluated in both groups. Results The scorings of nervous function defect in treatment group on the 7 th，14 th，28 th day after treatment were significantly decreased，compared with those before treatment (P0.01)，so did with those of control group (P0.01). There was a significant difference in scoring of nervous function defect in control group on the 14th，28th day before treatment and after treatment (P0.01). The therapeutic effect of treatment group was superior to that of control group, there were significant differences in effective rate and total effective rate between treatment group and co