2014 日本过敏性鼻炎指南.pdfVIP

Allergology International. 2014;63:357-375 DOI: 10.2332allergolint.14-RAI-0768 REVIEW ARTICLE Japanese Guideline for Allergic Rhinitis 2014 1 2 3 4 5 Kimihiro Okubo , Yuichi Kurono , Shigeharu Fujieda , Satoshi Ogino , Eiichi Uchio , Hiroshi Odajima6, Hiroshi Takenaka7 and Japanese Society of Allergology ABSTRACT Like asthma and atopic dermatitis, allergic rhinitis is an allergic disease, but of the three, it is the only type I al- lergic disease. Allergic rhinitis includes pollinosis, which is intractable and reduces quality of life (QOL) when it becomes severe. A guideline is needed to understand allergic rhinitis and to use this knowledge to develop a treatment plan. In Japan, the first guideline was prepared after a symposium held by the Japanese Society of Allergology in 1993. The current 7th edition was published in 2013, and is widely used today. To incorporate evidence based medicine (EBM) introduced from abroad, the most recent collection of evi- denceliterature was supplemented to the Practical Guideline for the Management of Allergic Rhinitis in Japan 2013. The revised guideline includes assessment of diagnosistreatment and prescriptions for children and pregnant women, for broad clinical applications. An evidence-based step-by-step strategy for treatment is also described. In addition, the QOL concept and cost benefit analyses are also addressed. Along with Allergic Rhinitis and its Impact of Asthma (ARIA), this guideline is widely used for various clinical purposes, such as measures for patients with sinusitis, childhood allergic rhinitis, oral allergy syndrome, and anaphylaxis and for pregnant women. A QA section regarding allergic rhinitis in Japan was added to the end of this guideline. KEY WORDS allergen immunotherapy, mechanism,