磷酸肌酸钠治疗小儿轮状病毒性肠炎合并心肌损伤68例的的疗效观察.docVIP

磷酸肌酸钠治疗小儿轮状病毒性肠炎合并心肌损伤68例的的疗效观察 　　摘要：目的观察磷酸肌酸钠治疗小儿轮状病毒性肠炎合并心肌损伤的临床疗效。方法将68例轮状病毒性肠炎合并心肌损伤患儿随机分为治疗组和对照组各34例,两组均针对病因给予相应的综合治疗.此外,治疗组加用注射用磷酸肌酸钠静脉注射,对照组加用注射用维生素C静脉注射,1次/d,疗程7d。结果观察两组治疗后磷酸肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)均较治疗前明显下降(P0.01)。治疗组总有效率94.7%，对照组总有效率76.3%。两组有显著性差异(P0.05)。 结论磷酸肌酸钠治疗小儿轮状病毒性肠炎合并心肌损伤疗效显著,优于注射用维生素C。 　　关键词：磷酸肌酸钠；心肌损伤；轮状病毒性肠炎 　　Clinical Observation of 68 Cases with Myocardial Creatine Phosphate Sodium in the Treatment of Infantile Rotavirus Enteritis Injury 　　SU Hui-lan,LI Xia-lian,CHEN Shuang,WANG Hai-lin 　　(Department of Pediatrics,Xiamen University Affiliated Second Hospital of Fuzhou City,Fuzhou 361000,Fujian,China) 　　Abstract：ObjectiveTo observe the clinical efficacy of creatine phosphate treatment of children with rotavirus enteritis complicated with myocardial injury. Methods Children with rotavirus enteritis combined myocardial injury 68 cases were randomly divided into treatment group and control group 34 cases, the cause for the two groups were given corresponding comprehensive treatment In addition, the treatment group were treated with sodium phosphate injection muscle. intravenous injection, the control group were treated with injections of vitamin C intravenously once daily for 7 days. ResultsObserved after treatment, creatine kinase (CK), creatine kinase (CK-MB) decreased significantly compared with those before treatment (P0.01). Treatment group, the total effective rate was 94.7% in the control group, the total efficiency of 76.3%. There was a significant difference between the two groups (P0.05). ConclusionCreatine phosphate sodium combined treatment of children with rotavirus enteritis myocardial injury significant effect, superior injectable vitamin C. 　　Key words：Phosphate sodium; Myocardial injury; Rotavirus enteritis小儿腹泻是我国婴幼儿常见病、多发病, 以6个月 ~ 2岁婴幼儿发病率高,多发生在秋冬季节, 轮状病毒是最常见的病原体。轮状病毒性肠炎是由轮状病毒所致的急性消化道传染病。主要临床表现为急性发热、呕吐及腹泻。腹泻，排黄色水样便，无黏液及脓血，量多，一般5～10次/d，重者甚至脱水。除侵犯胃肠道呼吸道外，还可以引起其他脏器损伤，以心肌损伤最为常见。 　　1 资料与方法 　　1.1 一般资料 68 例患儿其病史, 临床表现, 实验室检查：白细