高压氧联合小剂量尿激酶治疗进展性脑梗死的的疗效观察.docVIP

高压氧联合小剂量尿激酶治疗进展性脑梗死的的疗效观察 　　doi：10.3969/j.issn.1007-614x.2014.9.8 　　摘 要 目的：探讨高压氧联合小剂量尿激酶在进展性脑梗死中的治疗效果。方法：收治进展性脑梗死患者126例，作为研究对象，随机将其分为两组，两组均予以监控血糖、血压、抗血小板凝集和预防并发症等常规治疗，对照组63例在此基础上联合尿激酶治疗，观察组63例则联合高压氧、尿激酶治疗，观察比较两组治疗效果。结果：观察组治疗后的Barthel指数（70.2±11.6）分，对照组（62.1±9.6）分，两组比较差异有统计学意义（P0.05）；观察组的总有效率95.24%，对照组82.54%，组间比较差异有统计学意义（P0.05）；观察组治疗后的血液流变学各项指标均明显好于对照组，治疗过程中未出现严重不良反应。结论：高压氧联合小剂量尿激酶在进展性脑梗死中的治疗效果显著，安全可靠。 　　关键词 高压氧 小剂量尿激酶 进展性脑梗死 疗效观察 　　Curative effect observation of hyperbaric oxygen combined with small dose of urokinase in the treatment of progressive cerebral infarction 　　Mao Naisheng 　　The central hospital in Zouping County，Binzhou City，Shandong Province，256212 　　Abstract Objective：To discuss the treatment effect of hyperbaric oxygen combined with small dose of urokinase in the treatment of progressive cerebral infarction.Methods：To admit 126 cases of patients with progressive cerebral infarction，as the research object，and were randomly divided into two groups，two groups were treated with conventional therapy，such as monitoring of blood sugar，blood pressure，antiplatelet aggregation and Prevent complications，63 cases in the control group based on this basis combined with urokinase treatment，63 cases in the observation group were combined with hyperbaric oxygen therapy，urokinase，to observe and compare the therapeutic effects of two groups.Results：Barthel index of the observation group after treatment was 70.2±11.6 score，the control group was 62.1±9.6，two groups had significant difference（P0.05）；the total effective rate of the observation group was 95.24%，82.54% in control group，the difference between groups was significant（P0.05）；all the indexes of hemorheology of the observation group after treatment were significantly better than that of the control group，no serious adverse drug reaction occurred during the treatment.Conclusion：The treatment effect of hyperbaric oxygen combined with small dose of urokinase in patients with progressive cerebral infarction is si