佛山市早产儿视网膜病诊治情况剖析.docVIP

佛山市早产儿视网膜病诊治情况剖析 　　【摘要】 目的：回顾性分析佛山市早产儿视网膜病变（ROP）的诊治情况，为更好防治早产儿ROP提供理论依据。方法：回顾分析本院新生儿科2013年1月-2014年12月出生胎龄34周组间，发病率差异有统计学意义（ 字2= 29.66，P0.005）；出生体重≤1000 g组、～1500 g组、～2000 g组间，发病率差异有统计学意义（ 字2=10.37，P0.05）；氧疗组早产儿ROP发病率较高（ 字2= 4.32，P0.05），机械通气组早产儿ROP发病率较高（ 字2=20.18，P0.005）。结论：佛山市ROP发病率为6.37%，低出生胎龄、低出生体重、氧疗、机械通气是ROP发病的重要危险因素。早期、规范、全程进行ROP筛查及诊治能够有效减少其发生率及改善预后。 　　【关键词】 早产儿； 视网膜病； 氧疗； 机械通气； 新生儿眼底筛查 　　Analysis of the Diagnosis and Treatment of Retinopathy of Prematurity in Foshan City/CHEN Zhao-yu，DAI Yi-heng，WU Ying-hua，et al.//Medical Innovation of China，2015，12（30）：036-038 　　【Abstract】 Objective： To retrospective analyze the diagnosis and treatment of retinopathy of prematurity （ROP） in Foshan，and provide a theoretical basis for the better prevention and treatment of ROP in premature infants.Method： The clinical data of 502 gestational age 34 weeks group，the incidence was statistically significant（ 字2=29.66，P0.005）；birth weightis less than or equal to1000 g group，-1500 g group，-2000 g group，the incidence was statistically significant（ 字2=10.37，P0.05）；the incidence of ROP of oxygen therapy group was higher（ 字2=4.32，P0.05），the incidence of ROP of mechanical ventilation group was higher（ 字2=20.18，P0.005）.Conclusion：The incidence rate of ROP was 6.37% in Foshan City，low gestational age，low birth weight， oxygen therapy，mechanical ventilation are important risk factors for the pathogenesis of ROP.The early，specification and whole process screening and treatment of ROP in preterm infants can effectively reduce the incidence and improve the prognosis. 　　【Key words】 Premature infant； Retinopathy； Oxygen therapy； Mechanical ventilation； Neonatal screening 　　First-author’s address：Foshan Maternal and Child Care Service Centre Affiliated to Southern Medical University，Foshan 528000，China 　　doi：10.3969/j.issn.1674-4985.2015.30.012 　　早产儿视网膜病变（retinopathy of prematurity，ROP）是指早产儿和低出生体重儿未发育成熟的视网膜血管异常发育和纤维增生导致的病变，可引起患儿视野缺损、视力下降、甚至失明的主要疾病之一[1]。多种因素可引起和促进ROP发病。其中常见的因素包括：多胎儿、低出生胎龄、