复方氟米松软膏治疗慢性湿疹临床疗效剖析.docVIP

复方氟米松软膏治疗慢性湿疹临床疗效剖析 　　[摘要] 目的 分析复方氟米松软膏治疗慢性湿疹临床疗效。方法 选取2015年1月―2017年1月该院收治的慢性湿疹患者125例，采用随机字母表法分为观察组与对照组，两组患者均给予常规治疗，对照组患者在此基础上采用曲安奈德益康唑乳膏，观察组患者在此基础上给予复方氟米松软膏治疗，对比两组患者特应性皮炎SCORAD评分、临床疗效、不良反应及复发率。结果 观察组患者治疗后SCORAD评分与对照组相比较低（P0.05）；观察组患者治疗总有效率96.83%显著高于对照组82.26%（P0.05）。结论 复方氟米松软膏治疗慢性湿疹临床疗效显著。 　　[关键词] 复方氟米松软膏；慢性湿疹；炎症评分；复发率 　　[中图分类号] R758.23 [文献标识码] A [文章编号] 1674-0742（2017）10（c）-0122-03 　　Analysis on Clinical Efficacy of Compound Flumetasone Ointment in Treatment of Chronic Eczema 　　LU Di 　　Department of Dermatology， Zibo First Hospital， Zibo， Shandong Province， 255000 China 　　[Abstract] Objective This paper tries to analyze clinical efficacy of compound flumetasone ointment in treatment of chronic eczema. Methods 125 cases of patients with chronic eczema treated in this hospital from January 2015 to January 2017 were random selected and divided into the observation group and the control group according to random alphabet method. Both groups were given routine treatment， on the basis of that， the control group was given triamcinolone acetonide and econazole nitrate cream， and the observation group was given compound flumetasone ointment. Atopic dermatitis SCORAD score， clinical efficacy， adverse reactions and recurrence rates were compared in the two groups. Results The SCORAD score in the observation group was lower than that in the control group（P0.05）. The total effective rate of the observation group was 96.83%， higher than that of the control group of 82.26%（P0.05）. Conclusion The clinical effect is obvious of compound flumetasone ointment in treatment of chronic eczema. 　　[Key words] Compound flumetasone ointment； Chronic eczema； Inflammation score； Recurrence rate 　　慢性?裾钗?慢性过敏性皮肤炎症，主要由急性或亚急性湿疹剧烈瘙痒、反复发作形成。皮肤因患者不断抓搔呈现局限性肥厚、苔藓样变或皲裂，且常伴随色素沉着。抗组胺药物及糖皮质激素类药物为慢性湿疹常用治疗药物，具有强效抗炎、止痒作用，但长期效果不理想，易复发，治愈困难[1]。因此，需寻找更为有效的治疗药物。复方氟米松软膏局部用甾体药物，具有良好抗炎、抗组织增生作用[2]。该研究中2015年1月―2017年1月收治的63例慢性湿疹患者采用复方氟米松软膏治疗，治疗效果明显优于常规西药治疗，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　在该院收治的慢性湿疹患者中随机选取125例