慢性咳嗽95例临床相关因素剖析.docVIP

慢性咳嗽95例临床相关因素剖析 　　【摘要】目的:慢性咳嗽病因复杂,迁延不愈,本文对可能导致慢性咳嗽的相关因素,特别是环境暴露因素的影响进行分析,为慢性咳嗽的病因学研究提供线索。方法:总结分析符合慢性咳嗽诊断标准的患者95例和对照组102例的基础临床资料并采用问卷调查过敏,既往呼吸道感染,环境烟草暴露,家庭人均居住面积等慢性咳嗽相关因素。结果:慢性咳嗽组的过敏史,既往呼吸道疾病住院史,环境烟草暴露因素均高于对照组。结论:在引起慢性咳嗽的致病因素中应特别关注环境烟草暴露问题。 　　【关键词】慢性咳嗽;影响因素;暴露 　　【中图分类号】R56【文献标识码】A【文章编号】1007-8517(2010)12-178-2 　　 　　Multi-variable analysis of factors affecting chronic cough in95 cases 　　【Abstract】Objective:To study the basic clinical data and environmental factors affecting chronic cough. We used pediatric patients to investigate the relationship between environmental tobacco smoke (ETS) exposure and chronic cough,for patients with chronic cough to provide clues to etiology. Methods:Summarized and analyzed in 2008 from February to December diagnostic criteria for chronic cough in 95 cases and the control group of 102 cases,were prospectively enrolled,in basic clinical data and using a questionnaire survey of allergies,past respiratory infections,environmental tobacco exposure,family per-capita living space,such as chronic cough related factors. Results:The outcome of patients with chronic cough group allergy history,past history of respiratory disease hospitalization,environmental tobacco exposure factors are higher than those of control group. Conclusions:In patients with chronic cough caused by pathogenic factors should be particularly concerned about exposure to environmental tobacco ETS played an important role in chronic cough in patients. 　　【Key words】Chronic cough;influencing factor;exposure 　　 　　咳嗽是呼吸科患者常见的症状之一,慢性咳嗽通常是指4周以上的持续或反复发作性咳嗽[1]。慢性咳嗽病因复杂,迁延不愈,严重影响生活质量。本文对慢性咳嗽的环境因素和临床特点进行了分析,进一步了解慢性咳嗽的特征,为慢性咳嗽的病因学研究提供更多的线索。 　　1对象与方法 　　1.1临床资料选自2007年5月～2008年6月在我院的门诊及住院患者95例,咳嗽持续时间4周～6个月。入选标准:咳嗽症状持续4周以上,伴或不伴其他临床症状,且均无明显影象学异常。排除标准:进入本研究前已明确诊断为哮喘或咳嗽变异型哮喘者。另有102例非慢性咳嗽的患有咳嗽症状的患者选入对照组;197例参与研究的对象中,男104例(52.8%),女93例(47.2%),男女比例为1.12:1。年龄23～74岁,平均年龄46.84±12.79,体重指数BMI13.6～30.1,平均22.23±3.50。见表1 　　表1 基础临床资料在慢性咳嗽组与对照组的比较 　　组别 性别 年龄 BMI 　　对照组 男57(55.9%)女45(44.1%) 46.9