糖尿病合并脑梗死血脂水平剖析.docVIP

糖尿病合并脑梗死血脂水平剖析 　　【摘要】目的 探讨2型糖尿病患者血脂水平与脑梗死的关系，以指导临床工作。方法 将合并脑梗死的2型糖尿病患者50例作为A组，与同期无血管病变的2型糖尿病患者48例作为B组，检测2组血清总胆固醇(TC)、甘油三脂(TG)、LDL-C(低密度脂蛋白胆固醇)、HDL-C(高密度脂蛋白胆固醇)、栽脂蛋白A(ApoA)、栽脂蛋白B100(ApoB100) ，并进行分析。 结果 2组间TC差异无显著性(P0.05), TG、LDL-C、HDL-C、ApoA1、ApoB差异有显著性(P0.05)。结论 2型糖尿病患者的脂代谢异常与脑梗死有密切关系。 　　【关键词】糖尿病;脑梗死;血脂 　　 　　Analysis of the Blood Lipid Level of Patients with Erebral Infarction Complicated by Diabetes Mellit HAN Hong.(Qingbai Jiang People’s Hospital of Chengdu, Chengdu 610300,China) 　　【Abstract】Objective The perpose of the study was to explore the relationship between blood lipid level of patients with diabetes mellitus and cerebral infarction, and guide clinical therapy.Methods 50 cases of patients with erebral infarction complicated by type 2 diabetes mellitus were divided into A group , 48 cases of corresponding period of type 2 diabetes mellitus patients without vascular complications were divided into B group. The serum total cholesterol(TC) ,three acids glyceride(TG), low-density lipoprotein cholesterol (LDL-C)， high-density lipoprotein cholesterol（HDL-C），apolipoprotein A (ApoA), apolipoprotei B100(ApoB100) of the two groups were detected and analyzed. Results There was no significant difference in TC between two groups (P0.05), but there were significant differences amound TG、LDL-C、HDL-C、ApoA1、ApoB(P＜0.05).Conclusion There was a close relationship between abnormal lipid metabolism of patients with diabetes mellitus and cerebral infarction. 　　【Key Words】Diabetes mellitus;Cerebral infarction;Blood lipid 　　【中图分类号】R587.1 　　【文献标识码】A 　　【文章编号】1814-8824(2009)-05-0022-02 　　 　　 糖尿病脑梗死是内科常见病、多发病，发病率有逐年上升趋势。我们对我院2006~2008年确诊为糖尿病合并脑梗死的患者50例与同期无糖尿病脑梗死48例的血脂水平进行分析，以了解血脂变化与发病的关系。 　　 　　1 资料与方法 　　 　　1．1 临床资料 糖尿病合并脑梗死组(A组):50例,男27例,女23例。平均年龄(64±6.93)岁。脑梗死经头颅CT或MRI检查确诊，糖尿病的诊断按WHO标准确诊为2型糖尿病。糖尿病不合并脑梗死组(B组):48例, 男25例,女23例。平均年龄(67±6.35)岁,为同期门诊的糖尿患者,头颅CT未见异常。 　　1．2 方法 授试者前3天无高脂食物史，均空腹抽取肘静脉血 ，检测血清总胆固醇(TC)、甘油三脂(TG)、LDL-C(低密度脂蛋白胆固醇)、HDL-C(高密度脂蛋白胆固醇)、载脂蛋白A(ApoA)、载脂蛋白B100(