阿奇霉素治疗社区获得性肺炎64例疗效剖析.docVIP

阿奇霉素治疗社区获得性肺炎64例疗效剖析 　　[摘要] 目的 探讨阿奇霉素治疗社区获得性肺炎的临床效果。方法 将我中心收治的68例社区获得性肺炎患者，随机分为对照组和观察组。对照组采用头孢呋辛治疗，观察组采用阿奇霉素治疗。比较两组的治疗效果，治疗前后肺部指标改善情况及不良反应发生情况。结果 对照组治疗总有效率79.4%，观察组总有效率97.1%。观察组总有效率显著高于对照组，差异有统计学意义（P0.05）。结论 阿奇霉素治疗社区获得性肺炎疗效显著优于头孢呋辛，主要临床症状及生化指标改善情况优于头孢呋辛治疗，细菌学转归显著优于头孢呋辛，使用方便，不良反应少，值得临床推广应用。 　　[关键词] 阿奇霉素；头孢呋辛；社区获得性肺炎；治疗 　　[中图分类号] R563.1 [文献标识码] B [文章编号] 2095-0616（2013）22-80-03 　　Efficacy analysis on azithromycin in the treatment of 64 cases with community acquired pneumonia 　　LIU Yong 　　Daqiao Community Health Service Station of Gulou District in Nanjing City，Nanjing 210015，China 　　[Abstract] Objective To study the clinical effect of azithromycin in the treatment of community acquired pneumonia. Methods Sixty-eight cases with community acquired pneumonia admitted in our community health service station were randomly divided into the control group and the observation group. The patients in the control group were treated with cefuroxime， while the patients in the observation group were treated with azithromycin. The treatment effect， improvement of pulmonary indexes before and after the treatment and adverse reactions of two groups were compared. Results The total effective rate of the control group was 79.4%， while that of the observation group was 97.1%. The total effective rate of the observation group was significantly higher than that of the control group， the difference was statistically significant（P0.05）. Conclusion The curative effect， improvement of major clinical symptoms and biochemical indicators and outcome of bacteriology of azithromycin in the treatment of community acquired pneumonia were significantly better than those of cefuroxime， and it is easy to use and has less adverse reactions， and is worthy of clinical application. 　　[Key words] Azithromycin；Cefuroxime；Community acquired pneumonia；Treatment 　　社区获得性肺炎（community acquired pneumonia，CAP），是指医院外罹患的感染性肺实质炎症，明确潜伏期的病原体感染入院后平均潜伏期内发布的肺炎也属于社区获得性肺炎，为呼吸科常见感染性疾病之一[1]。目前临床主要采用抗生素类药物治疗，但长期大剂量使用抗生素易