磁纳米粒子弱磁测量系统设计-控制工程专业论文.docx

华中科技大学硕士学位论文 华 中 科 技 大 学 硕 士 学 位 论 文 II II Abstract The thesis aims to design a weak magnetic field measurement system employing magnetoresistive sensor HMC1022 in order to measure magnetic nanoparticles’ magnetization or magnetic susceptibility so that some magnetic characteristics such as thermal dynamic behaviors can be investigated. And the homemade measurement system has a great significance in the development of magnetic nanoparticles in biomedical applications such as MR contrast agents, cancer hyperthermia and nanoparticle temperature estimation. Firstly, employing the research and analysis on weak magnetic field measurement system, in addition to summarizing the sensor characteristics of weak magnetic field measurement such as performance parameters, manufacturing design and production cost, the thesis takes into account the requirements of weak magnetic field measurement upon magnetic nanoparticle. At last, the magnetoresistive sensor HMC1022 is selected to measure the magnetization of magnetic nanoparticles. Secondly, hased on the characteristics parameters of magnetoresistive sensor HMC1022, the zener diode TL431 and MOS FET IRF7105 are used to design the drive and set/reset electronic circuits, respectively. Then the output signal from sensor HMC1022 is amplified by the instrumentation amplifier AD620. At last, the single-end signal is transformed to differential signal, which will be inputted into the Data Acquisition Card. At last, using the data acquisition card produced and the LabVIEW software development platform, the thesis designs a software system with data acquisition, data processing such as digital phase sensitive detection algorithm and data preservation in order that it can acquire the real-time magnetization amplitude of magnetic nanoparticles, and achieve a real-time display of the magnetic nanoparticles’ temperature versus inverse susceptibility curve, eventually save the experimental data. The homemade system is used as a platform for