复合中药制剂局部应用辅助治疗慢性牙周炎临床效果评价-口腔临床医学专业论文.docx

万方数据 万方数据 目 录 中文摘要 ·············································································1 英文摘要 ·············································································3 英文缩写 ·············································································5 研究论文 复合中药制剂局部应用辅助治疗慢性牙周炎临床效果评价 前言 ·············································································6 材料与方法 ····································································8 结果 ·············································································13 附表 ·············································································14 讨论 ·············································································17 结论 ·············································································22 参考文献 ·······································································23 附录 ·············································································26 综述 中药制剂辅助治疗慢性牙周炎的研究进展 ····························30 致谢 ···················································································37 个人简历 ·············································································38 中 中 文 摘 要 PAGE 10万方数据 PAGE 10 万方数据 复合中药制剂局部应用辅助治疗慢性 牙周炎临床效果评价 摘 要 目的: 牙周炎是慢性感染性疾病，菌斑微生物是其始动因子。近年来 对于慢性牙周炎的临床治疗主要是牙周基础治疗，如龈上洁治、龈下刮治 等机械治疗方法，但牙周机械治疗具有一定的局限性，在有些情况下需要 合理配合使用药物。对牙周炎的药物治疗主要是全身用药和局部用药，全 身用药多数为口服抗生素，局部用药大多也是化学合成的抗菌冲洗、含漱 药物，但长期全身和局部应用抗生素会导致机体菌群失调，产生耐药性， 并且容易造成变态反应。而中药适应症广泛，产自天然，副作用较少，为 了研究中药制剂局部治疗慢性牙周炎的临床疗效，阐述中药在牙周炎局部 治疗中的应用，本实验拟采用清热解毒、抑菌的中药材按照中医经验方剂 配制复合中药制剂药膏，局部治疗慢性牙周炎，以观察其对慢性牙周炎临 床指标的影响，为中医中药方法局部辅助治疗慢性牙周炎提供临床参考。 方法： 1 病例选择 选取 20 例慢性牙周炎病患者，均来自 2015 年 02 月至 2015 年 8 月在 ―河北省石家庄市第二医院‖口腔科就诊的患者，患者年龄在 30 岁-56 岁之 间，平均年龄为（44.3±3.46）岁。采用随机数字表法将其随机分为两组， A 组为复合中药制剂实验组 10 例，B 组为观察对照组 10 例，每例患者选 取 3 颗牙齿作为观察牙，分别是一颗切牙，一颗前磨牙，一颗磨牙，即每 组 30 颗牙齿作为观察对象，两组进行比较。选取口腔内牙周袋探诊深度 ≥3mm 并且 X-Ray 显示牙槽骨不同程度吸收、破坏的牙齿作为观察对象。 将所配制的中药制剂―牙周清热抑菌中药软膏‖，应用于基础治疗后的牙周 袋，在治疗期间，对患者的牙周恢复情况进行跟踪记录，从而对―牙周清 热抑菌中药软膏‖的治疗效果和作用进行评估。 2 记录牙周主