复方芪鹰颗粒在糖尿病周围神经病变中的临床应用研究-内科学(内分泌与代谢病学)专业论文.docx

新疆医科大学硕士学位论文 新疆医科大学硕士学位论文 - - 复方芪鹰颗粒在糖尿病周围神经病变的临床应用研究 研究生：梁健 导师：胡晓灵 主任医师 张磊 副主任中医师 摘 要 目的：探讨复方芪鹰颗粒治疗糖尿病周围神经病变的有效性。方法：75 例糖尿 病周围神经病变患者，随机分为两组。在常规治疗基础上，实验组 40 例，给予复方 芪鹰颗粒治疗；对照组 35 例，给予糖脉康颗粒治疗。观察患者治疗前后临床症状、 空腹血糖、餐后两小时血糖、神经传导速度及综合疗效。结果：治疗组和对照组患 者临床症状及血糖均有改善，治疗组综合疗效优于对照组（P 0.05）；治疗组降低 空腹血糖疗效优于对照组（P 0.05）。治疗组用药后神经传导速度较对照组提高， 有统计学意义（P 0.05）。结论：复方芪鹰颗粒可改善糖尿病周围神经病变患者临 床症状，加快感觉及运动神经传导速度，改善糖代谢异常。 关键词：复方芪鹰颗粒；糖尿病周围神经病变；临床应用研究 Clinical Application Study on Healing Effect of DPN of Fu Fang Qi Ying Postgraduate: Liang Jian Supervisor: Prof. Hu Xiaoling Prof. Zhang Lei Deputy Direct of TCM Abstract Objective：To observe the clinic curative effect of Diabetic Peripheral Neuropathy（DPN） and discuss the mechanism of action by formulation of Fu Fang Qi Ying.Method：In clinic application study，75 cases of Diabetic Peripheral Neuropathy were divided into two groups at random,treatment group(n=40)and control group(n=35).The treatment group were treated with granular formulation of Fu Fang Qi Ying,while the control group with granular formulation of Tang Mai Kang.Four weeks later，we observed the effect on the patients.Observing the symptoms and total effective ratios,making measurement of FBG,2HBG and NCV before and after the treatment.Results：After four weeks of treatment,both the symptom and BG for patients of two groups are improved.The clinic synthetic effectiveness in the treatment group is better than the control group,and the effect of treatment group to reduce FBG is better than the control group,the differences are significant(P 0.05).The NCV in the treatment group wasaccelerated than the control group,the differences are significant(P 0.05).Conclusions：The granular formulation of Fu Fang Qi Ying can obviously improve the patients’ clinical syndrome,accelerate NCV and reduce BG.May be it is one of the mechanism of actions to treat DPN by the granular formulation of Fu Fang Qi Ying. Key words：Granular formulation of Fu Fang Qi Ying;DPN; Clinical application study 中英文缩略词对照表 英文缩写