肝脏的不规则模拟切除—设计与实现-生物医学工程专业论文.docxVIP

华中科技大学硕士学位论文 华 中 科 技 大 学 硕 士 学 位 论 文 II II Abstract Liver cancer is the one of the diseases having high mortality rates. Currently, the preferred method for the treatment of liver cancer is hepatectomy. Surgery plan designing, path planning and plan evaluation before surgery are important to improve the efficacy of hepatectomy. We designed and simulated the liver virtual resection in computer-aided liver surgery planning, so that doctors can plan cutting path, choose reasonable surgery plan to improve the effect of treatment of liver cancer to satisfy the requirements of nonanatomical hepatectomy. According to different cases and different needs, we designed and implemented three functions : virtual plane resection, virtual multiple plane resection and virtual curve resection. Through observing the three-dimensional liver, tumor and blood vessel model, the user select cutting mode and determine the cutting planes. Virtual resection can be ultimately completed by translating and rotating the cutting planes, also deformation operation, then the user can analyze and evaluate the surgery plan. We used principal component analysis algorithm and needling picking algorithm to determine the cutting planes. Then cutting planes were modified through geometric transformation and Bezier surfaces. And we used three-dimensional region growing algorithm and bilinear interpolation algorithm to mark volume data. The study aimed to provide a computer-aided treatment means for the surgical treatment of liver cancer. Through cooperation and communication with the radiologists, the design took the actual needs of users into account, and virtual cutting process simulated liver cancer surgery vividly. And the interaction process is simple, to ensure users completing the surgery planning in a short time efficiently. Finally, we used clinical CT data to validate and evaluate the system. We could see the process was fast and convenient, updating of models drawn was time saving, III III he