肺腺癌EGFR基因突变与EGFR蛋白和EGFR突变特异性抗体表达情况及意义-病理学与病理生理学专业论文.docxVIP

福建 福建医科大学 2011 级硕士研究生毕业论文 万方数据 万方数据 目 录 英文缩写词对照表 ·················································································1 中文摘要······························································································2 英文摘要······························································································4 前 言···································································································6 第一部分 肺腺癌 EGFR 基因突变及其临床意义 材料和方法 12 结果 ····································································································18 讨论 ····································································································21 结论 ···································································································· 23 第二部分 肺腺癌 ERFG 蛋白和 EGFR 突变特异性抗体的表达及其临床意义 材料和方法···························································································24 结果 ····································································································28 讨论 ····································································································36 结论 ···································································································· 39 参考文献······························································································ 40 综述 ···································································································· 45 致谢 ···································································································· 55 攻读学位期间发表的论文及获奖情况 ······················································· 56 3 英文缩写词对照表 英文缩写 英文全称 中文全称 NSCLC Non-small cell lung cancer 非小细胞肺癌 EGFR Epidermal growth factor receptor 表皮生长因子受体 TK Tyrosine kinase 酪氨酸激酶 EGFR- TKIs Epidermal growth factor receptor- 表皮生长因子受体-酪 tyrosine kinase inhibitors 氨酸激酶抑制剂 del EGFR deletion in exon 19 of EGFR 表皮生长因子受体 19 外 显子缺失 L858R-EGFR L858R mutation in exon 21 of EGFR 表皮生长因子受体 21