dbc2在幽门螺杆菌相关胃癌生长和侵袭转移中的作用及机制研究-临床医学（内科学·消化系病）专毕业论文.docx

山东大学博士学位论文4．本章小结 山东大学博士学位论文 4．本章小结 ．．58 第四部分DBC2对感染Hp的胃癌细胞SGC7901侵袭转移能力和趋化因子受体 CXCR4影响的实验研究 59 1．材料与方法 ．59 3．讨论 64 4．本章小结 ．．67 结论 ．．68 附图表 69 参考文献 97 综述 ．118 致谢 ．1 27 攻读学位期间发表的学术论文目录 128 学位论文评阅及答辩情况 129 外文论文 1 30 万方数据 山东大学博士学位论文CoNTENTS 山东大学博士学位论文 CoNTENTS Abstract in Chinese l Abstract in English · ·’7 Abbreviating Words‘·········__·‘······‘-··-·····-1····’····-·‘··’·’·····‘·‘·’·-··-1···············_’·。·················‘·················’··-······‘14 Reface · · -1 5 Text： Part I．The expression status of tumor suppressor gene DBC2 in gastric associated with Helicobacter pylori and its clinical significance ·······，··，···········t--······················· ···········，············-··················t，·-·······t·····-·--·-······，······，···············--20 Materials and Methods -- ● ··20 Results··-··········，，··················_·······-········，···············_························-···········_·······_·····························。··········’30 Discussions · ·‘3 l Conclusions ·· ·· ’34 Part II．The construction and transfection of recombinant oVerexpression vector of exogenous DBC2 gene in SGC7901 cells ．．．．．．．．．．．．．．．．．．．．．．．， ．．．．．．．．．．，，．，．．．．．．．．．．．．．．．．．．．．． ··························tt- 35 Materials and Methods 35 Results 4 l Discussions 44 Conclusions 46 Part IlI．Study the proliferation and apoptosis of gastric cell infected Helicobacter pyiori caused by DBC2 intervention ．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．-．．．．．·································-一-········-··-·····-·········-·，··················48 万方数据 山东大学博士学位论文Materials 山东大学博士学位论文 Materials and Methods··················-·····················t·········-··-···-·······································” 48 Results · ·53 Discussions ·55 Conclusions 58 Part IV．Experimental study invasion and metastasis of gastric cell infected Helicobacter pylori caused by DBC2 intervention 59 Materials and Methods 一59 Results ．63 Discussions 64 Conc