《川芎药用成分的提取及含量测定》-毕业论文设计（学术）.docVIP

PAGE V 川芎药用成分的提取及含量测定 摘要：川芎又名芎穷、西芎、京芎、杜芎、小叶川芎等。科属为伞形科藁本属，多年生草本植物。川芎以根茎入药，现代临床上用于治疗心脑血管系统、血液系统等疾病。本实验以含量较高的活性成分阿魏酸为评判指标，先对提取溶剂和提取方法进行筛选，然后以溶剂浓度、溶剂加量和提取时间为考察因素进行用正交设计实验对川芎的提取工艺条件进行优化。结果表明，从川芎中提取阿魏酸，用乙醇作为溶剂要优于甲醇、丙酮，以热回流法提取优于超声提取法、索氏提取法。正交设计实验表明最佳提取工艺条件为10g川芎生药粉用150ml的80%乙醇提取3h。 本实验对筛选出的最佳工艺条件进行了验证，表明了筛选出的最佳工艺条件具有一定的可行性，具有较高的稳定性，而且所提取的有效成分含量比其他方法高。 关键词：川芎; 阿魏酸; 正交设计; 最佳工艺; 含量 Extraction and Assaying of Medicinal ingredients in Ligusticum Chuanxiong Hort Abstract: Chuanxiong was also named Xiongqiong, Xixiong, Jingxiong,Duxiong, Foliolum Chuanxiong. The Branch of Chuanxiong is Umbelliferae Ligusticum and Chuanxiong is a perennial herb. The medicinal part of Chuanxiong is rhizome, Modern clinical practice for the treatment of cardio-cerebral vascular system, blood system diseases and so on. In this experiment with higher levels of the active ingredient of ferulic acid for evaluation indicators, First screening the extraction solvent and extraction methods, And then with the dissolvent concentration, dissolvent volume and extraction time for the study of factors to optimized extraction conditions of Chuanxiong by orthogonal test. The results showed that The ferulic acid extracted from Chuanxiong , ethanol is superior to methanol,acetone as a solvent, heat reflux extraction method is superior to ultrasonic extraction, Soxhlet extraction method.The optinmm extraction processes of extracting ferulic acid from Chuanxiong was adding 150ml of 80％ alcohol，refluxing and extracting 3 hour for 10g. This experiment verify to the optimum conditions,showed that optimum conditions possess the feasibility , certain high stability, and the extraction of active ingredients than any other method. Key words：chuanxiong，ferulaic acid，orthogonal design，optimization artwork，contents 目 录 TOC \f \h \z \t 标题 2,1,标题 3,2,标题 4,3 HYPERLINK \l _Toc230918736 第1章 绪 论 PAGEREF _Toc230918736 \h 1 HYPERLINK \l _Toc230918737 1.1 川芎的概述 PAGEREF _Toc230918737 \h 1 HYPERLINK \l _Toc230918738