专家幻灯—偏头痛病理生理(于生元).pptVIP

Key point: A secondary neuroinflammatory cascade could be generated in the dura involving the release of inflammatory mediators such as NO and the neuropeptides CGRP and substance P, which could contribute to the pain of migraine. 二次神经炎性在硬脑膜形成，涉及炎性递质的释放，包括NO，神经递质CGRP，P物质等，促使偏头痛疼痛。 It has been hypothesized that neurogenic inflammation develops in dura mater induced by the release of various vasoactive neuropeptides from trigeminal perivascular fibers, leading to a cascade of events characterized by vasodilation, plasma protein extravasation, and the release of proinflammatory mediators.假设激活的三叉