内科学概论如心脏血管内科.ppt

* * * * * * * * * * * * * * On the left is a scanning electron micrograph (SEM) of adherent platelets. Platelets adhere to cell surfaces through their cell surface adhesion molecules and membrane receptors such as glycoprotein Ib/IX (GP Ib/IX), the ligand for von Willebrand factor. On the right is an SEM showing aggregated platelets forming a first hemostatic plug. When activation occurs, the glycoprotein IIb/IIIa membrane receptor (GP IIb/IIIa) is exposed. This receptor forms bridges using fibrinogen, which result in platelet aggregation. Without this aggregation, the platelet plug would rapi