临床医学毕业手术治疗与保守治疗出血型烟雾病远期疗效对比.docVIP

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临床医学毕业手术治疗与保守治疗出血型烟雾病远期疗效对比.doc

临床医学毕业手术治疗与保守治疗出血型烟雾病远期疗效对比.doc

XX大学 毕业论文 手术治疗与保守治疗出血型烟雾病远期疗效对比 姓 名: 2014年6月25日 作者:邸飞赵继宗张东王江飞 【关键词】长期随访, 【摘要】目的 比较手术及保守治疗出血型烟雾病疗效的差异。方法 选 择1997年4月?2002年2月收治的岀血型烟雾病患者53例,分为手术组(24 例)以及保守治疗组(29例)。分析全部患者的临床、影像学资料,并对所有病 例行横断面式随访调查。结果 共随访到患者36例,发现两组患者目询恢复情 况、再出血率以及缺血性症状发生率差异均无显著性(P0.05)。结论 对于出 血型烟雾病患者,针对于烟雾病本身的手术治疗(尤其是非直接搭桥手术),与 保守治疗相比,并无明显优势,选择时应十分慎重。 关键词 烟雾病出血型长期随访疗效评估 Long-term effects of surgical therapy and conservative treatment on moyamoya Di Fei, Zhao Jizong, Zhang Dong, et al. Neurosurgery Department, Tiantan Hospital, Beijing 100050. 【Abstract ] Objective To judge if surgery therapy merely aimed at moyamoya disease itself is applicable for hemorrhagic moyamoya disease patients by analyzing and comparing the long term prognosis between groups of patients receiving conservative or surgery trcatmcnt.Mcthods Total53hcmorrhagic moyamoya disease patients were hospital-ized in our hospital from April 1997to Febmary2002.They were divided into two groups:in group I there were24patients, who received surgery therapy;in group II there were29patients , who only received conservative treatment.Their clinical and image data were retrived and retrospective calls on were carried out for all patients transversely from September to December2003.Results There arc no significant difference between surgery and conservative treatment in present convalescent condition, rate of re-hemorrhage and rate of ischemic symptom occurrence.Conclusion Surgery therapy should be chosen very cautiously for patients of hemorrhagic moyamoya disease. Key words moyamoya disease hemorrhagic long tenn follow up assessment of therapeutical effect 烟雾病(moyamoya病)是指双侧颈内动脉末端的特异性阻塞性疾病,患 者于颅底出现大量细小的侧支循环血管,在血管造影吋呈现为模糊不清的烟雾 状,故称moyamoya病。其临床表现可分为缺血型与出血型两类,成年患者以后 者多见[1]。在神经外科的临床工作屮,出血型患者较常见,症状相对严重, 对于此类患者,治疗方法及效果尚无公认的规范,我院门1997年4月?2002年 2月期间,共收治岀血型烟雾病患者53例,本研究将出血型烟雾病的手术治疗 与保守治疗远期疗效进行了比较,以求验证两种治疗方法对改善患者的症状、防 止再出血及缺血症状的发牛有无显著性意义。 1对象与方法 1.1研究对象1997年4月?2002年2月,我院共收治烟雾病患者161例, 其中岀血型烟雾病患者53例,占全部烟雾病患者的32.9%。将全部患者分为两 组:1组,进行针对烟雾病手术的出血型烟雾病患者组,共冇24例(男1

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