反复应用碘消毒剂可否导致人体过量摄碘的研究外科学血管外科专业论文.docxVIP

复旦大学硕：l=学位论文 复旦大学硕：l=学位论文 中文摘要 中文摘要 背景：以碘元素为有效成分的消毒剂在医学领域有着广泛的应用。外科医生在术前 进行手部消毒时，含碘消毒剂一直是在世界范围内最经典的、应用最广的选拶11。碘元 素同时是甲状腺激素的合成原料，碘的缺乏可引起多种甲状腺疾病。2001年以来，人 们开始认识到，碘的摄入过量同样可使多种甲状腺疾病的发病率增加圆目的：探讨外科 医生反复应用含碘消毒剂进行术前手部消毒是否会引起碘元素过量摄入。方法：使用国 际公认的测定方法对上海中山医院长期使用安尔碘刷手的外科医生和器械护士的碘摄 入水平进行测定，并在该医院使用新型消毒剂替换安尔碘之后对同样的样本再次进行了 测定，作为自身对照。结果：经过对71例样本和61例对照样本的结果分析，发现该人 群并不存在碘摄入过量，并且停用含碘消毒剂后该人群碘的摄入水平亦无显著下降。 关键词：碘安尔碘甲状腺疾病经皮吸收洗手 中图分类号：R181．3+1，R613 复日大学硕士学位论文 复日大学硕士学位论文 英文摘要 Abstract Background：Disinfectants containing iodine are widely used in medicine fien It has been most commonly chosen by surgeons as the classic disinfectant for pre-operative scrub．Iodine is also a material for the thyroid gland tO produce thyroid hormone，and the inadequate intake of iodine has been known tO contnbute tO thyroid diseases．On the year 2001，it was known that the overdosed intal‘e of iodine can also cause many kinds of thyroid diseases．Object：To determine whether repeated use of iodine as surgery scrub will causes overdosed intake of iodine．Metllods： Determine the level of iodine intake of a group of surgeons and scrub nurses in Zhongshan Hospital who have been intensively us洒g iodine as per-operative hand scrub，Then run the test again tO the same group of people as a self-control after the hospital rephced the disinfectant with a new one without iodine，and contrast the results of the two times．Results：After analyz矗ag the result from the specimen of 7 1 people and their self-control,it is believed that tIle intensive use of disinfectant with iodine does not cause overdosed iodine intake，and that after stop using it there is no significent decrease of tIle level of t11e iodine intake． Key Words：Iodine，Thyroid Disease，Transdermal Absorption，Surgery Scrub CLC：R181．3+1，R613 Z 复旦大学硕士学位论文 复旦大学硕士学位论文 引言 引言 碘是人体合成甲状腺激素的主要原料，碘的摄入量与甲状腺疾病的发病密切相关。 碘摄入不足引起的甲状腺疾病早己被大家所熟知，许多国家和