重金属污染对儿童智力的影响.doc

. .. 丰台区256名小学生体内重金属含量与智力和神经行为的相关性分析① 石荣兴 芦 然 吴 岩 程紫薇 赵建忠② 李 洁 北京市丰台区疾病预防控制中心（北京）100071 【摘要】 目的：了解丰台区学龄儿童体内重金属分布现状及其与儿童智力发育和神经行为的相关性。方法：采用整群随机抽样的方法，随机抽取丰台区3所小学校的9-12岁的学龄儿童256名作为研究对象，进行文智力测验、神经行为测验、血样和尿样中铬、镍、砷、硒、镉、汞、铊、铅含量检测。结果：256名儿童血铅、血硒、尿砷检出率为100%,铊检出率为0,其他金属的检出率在10.3%至71.1%之间，儿童血铬、血硒、血铅，尿硒含量与IQ正相关(P＜0.05)；血汞、尿汞与IQ负相关(P＜0.05)；儿童血砷、尿砷、尿铬、尿铅、尿硒与神经行为负相关(P＜0.05)。结论：研究区域儿童体内各金属均有检出应引起重视；汞对儿童的智商发育有不良的影响；硒对儿童智商有保护作用；金属砷，铬，硒，铊，铅对儿童神经行为发育有不良影响。 【关键词】 重金属 学龄儿童 智力发育 神经行为 The content of heavy metals in 256 students’ body and its’ Correlation analysis with intellectual and neurobehavioral in Fengtai District SHI Rong-Xing ,LU Ran，WU Yan et al。Center for Disease Prevention and Control of Beijing Fengtai District 【Abstract】 Objective: To understand the present situation of children’s heavy metals in Fengtai district, to discuss that influence of heavy metals in children’s intelligence development and neurobehavioral functions。Method: Random sampling was used to choose 3 primary schools in the study area, and choose 256 students from grade 3-5 at age of 9 to 12 of these three schools. All the students were investigated with CRT (the second version) and Jinyi PsychomotorTest Battery (JPB). The level of blood and urine lead(Pb),nickel(Ni),chromium(Cr),cadmium(Cd),thallium(Tl),mercury(Hg),arsenic(As),selenium(Se) in children was detected by ICP-MS method. Use Excel2003 to establish database and use the SPSS19.0 to do statistical analysis. Results: 256 childrens blood lead, blood selenium, arsenic in urine was 100% detection ，rate of thallium is 0, rate of other metal detection is between 10.3 to 71.1 percent, a childrens blood chromium, blood selenium, blood lead, selenium content in urine is positively correlated with IQ (P 0.05); blood mercury, urine mercury is negatively correlated with IQ (P 0.05); child blood arsenic, urinary arsenic, urinary chromium, lead in urine, urinary selenium is negatively correlated with neurobehavioral (P 0.05). Conclusion: the study area were det