超声提取中药复方的技术研究药剂学专业论文.docxVIP

中文摘要超声提取技术基有掇敬效率瘫、省时、程工蒋德点，但仅局限予单昧中药的 中文摘要 超声提取技术基有掇敬效率瘫、省时、程工蒋德点，但仅局限予单昧中药的 摇取，而中医厢药多以复方为主，药物发挥的是多成分、多靶点的综合治疗作用， 毽越声技零受裂了限裂，皆翡复方袋用藤声提取技术嚣赘述是令空鑫。摩麟究擞 用窝禽多糖类成分的六昧地觜复方为模型药物进行比较研究。以千膏收率、丹皮 酪禽震、惩多糖客繁、熊聚羧窘爨冀疆臻，搬鼹瘩、s溅乙蘸、95Y己簿三耱撵载 溶对超声、回流、渗漉三种掇取方法进行难突试验，筛选出九种不闯提取工艺的 最链提取条件。避行超声提敬法每翻流法、渗漉法猩薄藤蕊潮、含繁澜定及药效 学{式验方谣谶行比较研究，网时避镗超声憝体提取与超声分别提取懿魄较礤突t 以确定该类复方翘声提取猎的药物成分韵质变和爨褒规律，探讨超声提取技术 在谈蹙中笺复方懿逡惩投；褥对丸释提取工莲进行魄较磷窕，谈稳遮出穴舔遣黄 复方艇佳提取工艺条件。研究结粜袭明越声提取技沭提取效率高、省时、省工的 经纛蹰释逶爝手禽多糖类戚努鞍多靛孛骛复方，著褥蠢焱睬趣黄笺方熬最健捷彀 工就为60％己醇超声提取，即加10倍量初始温魔为60‘C灼60Y,z|醇对复方药树 襁耪遴行怒黟疆彀2次。每次38m酗，越声颓率为25k毪z。该王蕊条件稳窳、岔 理、可行，蜀失六喙邀黄复方割剃工艺改革提供镶搌。 关键词：超声提取技术 薄层撩别 含量测定 药效学试验 ABSTRACTU1trasonic ABSTRACT U1trasonic technology has advantage in extraction efficient、labour saving、time saving and so on．it has only application in extracting for a single traditional Chinese medieine plant。However prescription and selection of Chinese medicine is to rely mainlY on chinese compound recipe and drugs have a role to play in comparehensive treatment of disease with multi～components and multi—targets．Therefore。ultrasonic technology has been obtained+That is to say，chinese compound recipe has not been extracted by it at present。The research had been on鞋ith drugs model of Six—Ingredient Rehmannia Compound Recipe with abundant polysaccharide．With gangao—yield，the content of Paeono，polys8eohar{de and ursolic acid indexes。ultrasonic-extraction、refluxing—extraction、pereoaltion— extraction with the three extracting mediums as water、60％Ethanel and 95％Ethanol were adopted to study with orthogonal design，then gain nine better extracting methods．The extraction method谨ith ultrasonic technology was compared with refluxing—extraction、percoattion— extraction methods in TLC ldentification，Main Consti tuent Content Tests and Pharmacodynamic Tests．At the same time compare these indexes between ‘ultrasonic extraction zhengti’(extract the compound recipe together wi￡h ultrasonie method)and ‘“ltrasonie extraction fenbie’(extract every single medicine plant in the compound r