蓝莓多糖对衰老小鼠运动耐力及抗疲劳效果研究.pdfVIP

※营养卫生 食品科学 2014, Vol.35, No.21 249 蓝莓多糖对衰老小鼠运动耐力及抗疲劳效果研究 郑 飞 （河南省淮阳县卫生监督所，河南 洛阳 466700 ） 摘  要： D 研究蓝莓多糖（blueberry polysaccharides，BPs ）对 -半乳糖诱导衰老模型小鼠的游泳耐力和相关生理指 标的影响。将小鼠分为正常对照组、衰老模型对照组、BPs低、中、高剂量组，通过腹腔注射100 mg/ （kg ·d ） D （以体质量计） -半乳糖建立衰老模型，考察其对力竭游泳时间以及疲劳评价指标的影响。与模型对照组相比， P BPs 中、高剂量组能显著延长小鼠力竭游泳时间（ ＜0.05 ），BPs各剂量组对延长缺氧生存时间具有较好的效果； % % % P BPs低、中、高剂量组血乳酸含量分别较模型对照组降低了10.9 、2 1.2 、31.1 （ ＜0.05 ）。此外，BPs 中、高 剂量组小鼠剧烈运动后血尿素氮、血乳酸和丙二醛含量显著降低，BPs各剂量组小鼠的肝糖原、肌糖原含量和超氧 化物歧化酶、乳酸脱氢酶活性均显著升高，结果表明BPs具有极强的自由基清除能力及较好的抗疲劳作用。 D 关键词：蓝莓多糖； -半乳糖；抗疲劳；力竭游泳时间 Anti-fatigue Effect of Polysaccharides Extracted from Blueberry in Mice ZHENG Fei (Institute of Huaiyang County Health Supervision in Henan Province, Luoyang 466700, China) Abstract: The effect of polysaccharides extracted from blueberry (BPs) on exhaustive swimming time and related physiological indexes in aged mice induced by D-galactose was investigated. Mice were randomly divided into normal control group, aged model group, low-dose BP group, middle-dose BP group, and high-dose BP group. The aged model was induced by D-galactose at a dose of 100 mg/(kg·d) for 60 consecutive days. After the administration of BPs for 20 consecutive days, the exhaustive swimming time and fatigue indexes were determined. The results showed that BPs could extend the exhaustive swimming time, decrease the contents of BUN, BLA and MDA, and obviously increase the reservation of HG, MG, SOD a