健脾养血汤治疗慢性湿疹(脾虚血燥型)临床研究-中医外科学专业论文.docxVIP

１ １ 健脾养血汤治疗慢性湿疹（脾虚血燥型）临床研究 研究生：罗小军 导师：刘红霞主任医师 摘 要 目的 针对慢性湿疹病因病机，通过临床观察健脾养血汤治疗脾虚血燥型慢性 湿疹患者的红斑、丘疹、丘疱疹、浸润苔藓样皮损的改善情况、瘙痒程度等的变化， 验证其临床疗效，以进一步指导临床。方法 将符合慢性湿疹纳入标准的门诊及住 院患者 125 例，随机分为治疗组和对照组。治疗前对年龄、性别、病程及病情等基 础资料进行了比较，治疗组（66）例，给予内服健脾养血汤，局部配以中药外敷， 外擦黄连膏，疗程为 4 周。对照组（59）例:口服氯雷他啶胶囊(深圳海王药业)，局 部配以中药外敷， 局部外擦黄连膏。疗程为 4 周。整个试验遵循随机原则。治疗后 根据疾病疗效、自觉症状及皮损评分标准进行统计分析。结果 治疗组有效率为 89.39%，高于对照组有效率 55.93%（p＜0.05）；治疗组与对照组治疗后红斑、丘疹、 丘疱疹、浸润苔藓及瘙痒较前有改善（p＜0.01）。但治疗组症状改善更为明显。结论 健脾养血汤是治疗脾虚血燥型慢性湿疹有效方剂，其在临床症状的改善方面及疾病 疗效上均明显优于对照药氯雷他啶胶囊。 关键词：健脾养血汤；慢性湿疹；临床研究； ２ ２ Clinical Research On The treatment For Chronic Eczema(The Type Of Spleen-deficiency and Blood-dryness）With jianpiyangxue Decoction student: Luo xiao-jun, advisor :Liu hong-xia, (Department of Dermatology; Affiliated Traditional Chinses Medicine Hospital; Xin Jiang Medical University;Urmqi;China 830000) Abstract Objective : According to the cause and mechanism of chronic eczema ,to observe the effect of jianpijiedutang on the treatment of lesion improvement and itching extent so as to verify its clinic effect and make a further guide for clinic practice.Methods :125 patients with chronic eczema were divided randomly into the treatment group (66 cases) treated with JianPiRunFuZhiYang Decoction and the control group(59cases) treated with Loratadine capsule ,Both groups had given the same external treatment and four-weeks as a courses of treatment. The whole trial followed by random and single blind principle, Analyzed data based on effective and symptoms as well as PASI after treatment. Result: The effective rate in the treatment group were 89.39% significantly higher than that of the control group (55.93%)(p0.05). both of groups have improvement on skin lesion.(p0.01)，and the former is better.Conclusion: The JianPiYangXue Decoction has the notable effective for Chronic eczema, its improvement of clinical symptoms and effect are significantly higher than control group. Key words: JianPiYangXue Decoction; Chronic eczema; clinical research; 中英文