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脾虚—线粒体—有氧糖酵解—肿瘤关联病因病机新假说
·医学假说·
DOI:10.13276/j.issn.1674-8913.2016.01.006
“脾虚—线粒体—有氧糖酵解—肿瘤关联”
病因病机新假说
1,2 3 1 1 2
戎志斌 ,罗安明 ,姚乃礼 (中国中医科学院广安门医院,北京 100053; 石家庄市妇幼保健院,河
3
北 石家庄 050081; 武汉市新洲区中医院,湖北 武汉 431400)
“Spleen deficiency-mitochondria-aerobic glycolysis-tumor
relationship”: a novel hypothesis for the etiology and
pathogenesis of tumor
1,2 3 1
RONG Zhi-Bin , LUO An-Ming , YAO Nai-Li
1 2
Guang’anmen Hospital, China Academy of Chinese Medical Science, Beijing 100053, China; Shijiazhuang Maternal
and Child Health Care Hospital, Shijiazhuang 050081, China; 3Xinzhou Hospital of Traditional Chinese Medicine, Wuhan
431400, China
Abstract Nowadays tumor is one of the frequently occurring diseases with a highest fatality rate. In order to
【 】
understand the etiology and pathogenesis as well as in an attempt to improve the prevention and treatment of tumor, the
authors presented a novel hypothesis that there is a relationship of tumor with spleen deficiency, mitochondria and aerobic
glycolysis, based on the review of a great number of medical literatures and the conclusion of clinical experiences. The new
hypothesis provided theoretical basis for explaining the scientific connotation of “replenishing qi, invigorating the spleen
and strengthening the body to resist tumor” from the perspective of traditional Chinese medicine theory combined with
modern molecular biology.
Keywords tumor; cancer cell; spleen deficiency; mitochondria; aerobic glycolysis; novel hypothesis
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