膏摩法结合超声药物透入治疗颈源性肩背痛的疗效-中国现代应用药学.PDF

·临 床· 膏摩法结合超声药物透入治疗颈源性肩背痛的疗效观察  陈鹏，金尧，蔡鑫磊，周志锦，胡军飞，马弘毅(浙江医院，杭州 310013) 摘要：目的 观察膏摩法结合超声药物透入治疗颈源性肩背痛的疗效及相关效应因子的调节变化。方法 将符合要求的 96 例颈源性肩背痛患者随机分为2 组，治疗组48 例，对照组48 例。治疗组以膏摩法结合超声药物透入疗法，对照组采 用常规手法结合口服塞来昔布胶囊治疗。分别观察2 组治疗前后的疗效及相关炎性因子白细胞介素-1β受体拮抗剂、白细 胞介素-6 及肿瘤坏死因子的浓度变化，并参照标准进行临床疗效的评定。结果 治疗后2 组的血清白细胞介素-1β 受体 拮抗剂浓度均增加，治疗组增加程度大于对照组；2 组血清白细胞介素-6 浓度均有降低，治疗组降低程度大于对照组；2 组血清肿瘤坏死因子浓度均有降低，治疗组降低程度大于对照组。治疗组总有效率91.7% ，对照组总有效率75.0% ，治疗 组疗效优于对照组(P0.05) 。结论 膏摩法结合超声药物透入治疗颈源性肩背痛的疗效优于常规手法及服药，能调节血清 中白细胞介素-1、白细胞介素-6 和肿瘤坏死因子等的浓度，是治疗颈源性肩背痛较为有效的方法。 关键词：膏摩法；超声药物透入；颈椎病；效应因子 中图分类号：R969.4 文献标志码：B 文章编号：1007-7693(2013)06-0667-04 Clinical Observation on the Curative Effect of the Cervicogenic Shoulder and Backache by Cream Friction Law Combined with Ultrasonic Drug Penetration CHEN Peng, JIN Yao, CAI Xinlei, ZHOU Zhijing, HU Junfei, MA Hongyi(Zhejiang Hospital, Hangzhou 310013, China) ABSTRACT: OBJECTIVE To observe the curative effect of cream friction combined with ultrasonic drug penetration for treating cervicogenic shoulder pain and to observe the related effective factors regulation change. METHODS Randomly divide 96 patients suffering from cervicogenic shoulder and back pain into two groups, in which 48 patients were in treatment group, the other 48 patients in control group. Adopt cream friction combined with ultrasonic drug penetration for treatment group, and regular manipulation combined with oral administration of celecoxib capsules for control group. Observe effect and concentration change of these related inflammatory factors such as IL-1β receptor antagonist, IL-6 and TNF before and after treatment respectively. And estimate clinical effect based on reference standard. RESULTS After treatment, the concentration of IL-1β receptor antagonist in both groups increased, while in treatment group, it was more