课件：第4章 细菌的遗传与变异.ppt

GenoList genome browser ????????????????? GenoList The New Multi-Microbial Genome browser. ??????????????? SubtiList Bacillus subtilis strain 168 GenoList browser ????????????? Colibri Escherichia coli strain K12 GenoList browser ???????????????? TubercuList Mycobacterium tuberculosis strain H37Rv GenoList browser ????????????????? Leproma Mycobacterium leprae strain TN GenoList browser ???????????????? BoviList Mycobacterium bovis strain AF2122/97 GenoList browser ???????????????? BuruList Mycobacterium ulcerans strain Agy99 GenoList browser ??????????????? ListiList Listeria monocytogenes strain EGD-e and Listeria innocua strain CLIP 11262 Multi-GenoList browser ?????????????????????? LegioList Legionella pneumophila Paris strain and Legionella pneumophila Lens strain Multi-GenoList browser ?????????????? PyloriGene Helicobacter pylori strains 26694 and J99 Multi-GenoList browser ???????????????? MypuList Mycoplasma pulmonis strain UAB CTIP GenoList browser ???????????????????? CyanoList Synechocystis PCC6803 and Anabaena PCC7120 Multi-GenoList browser ?????????????????? AureoList Staphylococcus aureus strains N315 and Mu50 Multi-GenoList browser ??????????????? StreptoPneumoList Streptococcus pneumoniae strains R6 and Tigr4 Multi-GenoList browser ??????????????? SagaList Streptococcus agalactiae strain NEM316 GenoList browser ??????????????? PhotoList Photorhabdus luminescens strain TT01 GenoList browser ????????????????? CandidaDB Candida albicans strain SC5314 GenoList browser Circular representation of the sequenced S. aureus and S. epidermidis genomes. Each concentric circle represents genomic data for S. aureus (A) and S. epidermidis (B) and is numbered from the outermost circle to the innermost circle. The outermost circles indicate the genome coordinates in base pairs. 五、在测定致癌物质中的应用 Ames实验：Ames本人对300余种化学品进行的微生物诱变试验及动物诱癌实验对比。 凡能诱导细菌发生突变的物质都有可能是致癌物质。 Ames实验 六、在基因工程中的应用 基因工程是根据遗传变异中细菌可因基因转移和重组而获得新性状的原理设计的 切取目的基因→连接到载体上→转移到