血小板聚集功能测定及临床意义.ppt

* Compared to these three products, our product, Cilostazol, Pletaal inhibits both aggregation reaction and release reaction. Our product, Cilostazol, Pletaal being an inhibitor of PDE III, increases the cyclic AMP level in the platelets, thereby facilitating free calcium ions back to its storage granules. Since the free calcium ions are needed for the formation of GP IIb/IIIa complex and for the degranulation of the storeage granules containing the aggregating substances such as ADP, serotonin, TXA2, etc., both reactions are inhibited by our product, Cilostazol, Pletaal. * 血小板表面有很多受体与血小板的激