应用小剂量泼尼松治疗亚急性甲状腺炎患者的临床效果.docxVIP

应用小剂量泼尼松治疗亚急性甲状腺炎患者的临床效果 ［摘要］目的探讨亚急性甲状腺炎患者应用小剂量泼尼松 治疗的临床效果。方法 对2013年3月?2015年3月我院84 例亚急性甲状腺炎患者的临床资料进行统计分析。结果比较患 者治疗前后指标情况，治疗后观察组患者FT3 （6. 35土 1.67） pmol/L、FT4 (16.65±3. 53) pmol/L、TSH (2. 46±0. 41) u IU/L 与对照组患者 FT3 (6. 22 + 1.45) pmol/L、FT4 (17. 87±3. 99) pmol/L. TSH (2. 40±0. 42) u IU/L比较，差异无统计学意义 （P0. 05）；观察组患者治疗后发热、肿胀、疼痛、触痛症状消 失时间均明显少于对照组患者，差异有统计学意义（P〈0?05）。 观察组患者不良反应发生率（4. 76%）明显低于对照组（28. 57%）, 差异有统计学意义（x 2=8. 57143, P二0. 0034K0. 05）。结论 小 剂量泼尼松治疗亚急性甲状腺炎，患者发热、肿胀、疼痛、触痛 症状消失时间明显缩短，不良反应发生率较低，安全、有效，建 议临床广泛应用。 ［关键词］亚急性甲状腺炎；抗病毒治疗；小剂量泼尼松; 不良反应 ［中图分类号］R581.4 ［文献标识码］B ［文章编号］ 1673-9701 (2016) 24-0031-03 Department of Endocrinology, the First People，s Hospital of Jingdezhen City in Jiangxi Province , Jingdezhen 333000, China [Abstract] Objective To investigate the clinical effect of low-dose prednisone in the treatment of subacute thyroiditis? Methods The clinical data of 84 cases of patients with subacute thyroiditis in the hospital from March 2013 to March 2015 were statistically analyzed? Results The various indicators before and after treatment of the two groups were compared, after treatment, the observation group FT3 (6. 35 + 1. 67) pmol/L, FT4 (16. 65 土3. 53) pmol/L, TSH (2. 46±0.41) u IU/L compared with the the control group FT3 (6. 22± 1. 45) pmol/L, FT4 (17. 87 ± 3. 99 ) pmol/L , TSH ( 2. 40 ± 0. 42 ) u IU/L had no significant changes, the differences were not significant (P0. 05)； The duration of fever, swelling, pain, and tenderness of the observation group were significantly shorter than those of the control group (P0.05)? The incidence of adverse reactions of the observation group was 4.76%, which was obviously lower than that of the control group ( 28.57% ) , there was statistical significance ( x 2=8. 57143, P=0. 0034K0. 05)? Conclusion Low-dose prednisone can shorten duration of clinical symptoms such as fever, swelling, pain, and tenderness? It is characterized by high effective, safe and low incidence of adverse reactions, which is recommended widely use