硫普罗宁联合丹参注射液治疗酒精性肝病的临床效果分析.docxVIP

硫普罗宁联合丹参注射液治疗酒精性肝病的临床效果分析 杨汉泽 (四川省资阳市乐至县人民医院感染科四川乐至641500) 【摘要】目的：分析对酒精性肝病患者采用硫普罗宁与丹参注射液联合进 行治疗的临床疗效。方法：收集我院接诊的患酒精性肝病的80例患者，按照随 机、对照、双盲的原则将其随机分成两组：对照组包含40例患者，在常规治疗 的基础上加用丹参注射液进行治疗；研究组包含40例患者，在对照组的治疗基 础上加用硫普罗宁联合进行治疗。治疗结束后对两组患者的临床疗效进行评估比 较分析，并观察两组患者用药后的不良反应发牛情况。结果：研究组治疗的总有 效率87.5%,明显高于对照组的55.0% (P0.05)o结论：对酒精性肝病患者采 用硫普罗宁与丹参注射液联合治疗疗效显著，安全性较高，值得临床推广。 【关键词】酒精性肝病；硫普罗宁；丹参注射液；临床疗效 【中图分类号】R575 【文献标识码】A 【文章编号】2095-1752 (2016) 23-0058-02 Clinical effect analysis of tiopronin combined with Danshen injection in treating alcoholic liver disease Yang Hanze. The Peoplersquo;s Hospital of Lezhi County, Ziya ng City, Sichuan Provi nc? Lezhi 641500,China [Abstract】 Objective To investigate the clinical effect of tiopronin combined with Danshen injection in treating alcoholic liver disease. Methods 80 cases with alcoholic liver disease in our hospital were selected as study objects. They were divided into two groups according to random number table. 40 cases in control group and were given Danshen injection based on conventional treatment. 40 cases in observation group and were given tiopronin based on control group? Compared the clinical effect and adverse reaction rate of the two groups. Results Total efficiency of observation group (87.5%) was obviously higher than control group (55.0%), (P 0.05). Conclusion The effect of tiopronin combined with Danshen injection in treating alcoholic liver disease has sign讦icant effect and is worthy of wide application. [Key words] Alcoholic liver disease; Tiopr onin; Dan she n in jecti on; Clin ical effect 随着近年来人们物质生活水平的逐渐提高与饮食生活习惯的不断变化，酒精 性肝病的发病例数亦在逐年增加，已成为仅次于病毒性肝病的第二人肝脏疾病, 严重威胁了广大患者的身体生命健康[1-2]o因此，采用科学合理的治疗方案对酒 精性肝病患者进行及时有效的临床治疗显得尤为重要。本研究收集我院接诊的患 酒精性肝病的80例患者，给予硫普罗宁与丹参注射液联合治疗，效果较为满意， 现总结如下： 1 ?研究对象和方法 1.1研究对象 收集我院2014年1月?2015年12月间接诊的患洒精性肝病的80例患者进 行临床研究，纳入标准：(1) 80例患者均经临床症状、体征、实验室检查、病 理学检查与B超、CT等影像学检查明确诊断；(2)均无合并脑、心、肾等严重 器质性疾病者；(3)无合并造血系统疾病与精神病者；(4)均无对本研究相关药 物过敏者；(5)患者及家属均自愿参与本研究，且签署知情同意书。按照随机、 对照、双盲的原则将其随机分成两组：对照组包含40例患者，其中男性患者25 例，女性患者15例；最低年龄2