几种常见多酚类化合物对低压低氧环境下大鼠记忆能力保护效应及分子机制研究-营养与食品卫生学专业论文.docxVIP

第三军医大学博士学位论文Mm 第三军医大学博士学位论文 Mm Millimetre 毫米 MtDNA Mitochondrial DNA 线粒体DNA MYR Myricetin 杨梅素 NADH Reduced form of 还原型烟酰胺腺嘌呤二核苷酸 nicotinamide．adenine dinucleotid NDl NADH dehydrogenase subunit 1 NADH脱氢酶亚基1 NOR Normoxia 正常氧含量 Nrfl Nuclear respiratory factor 1 核呼吸因子1 0D Optical density 光密度 PAGE Polyacrylamide gel electrophoresis 聚丙烯酰胺凝胶电泳 PBS Phosphate buffered saline 磷酸盐缓冲液 PCR Polymerase chain reaction 聚合酶链式反应 PGC．1u subunit of peroxisome 过氧化物酶体增殖活化受体Y辅 proliferators—activated receptor—Y 助活化因子l Q coactivator-1 PMSF Phenylmethanesulfonyl fluoride 苯甲基磺酰氟 PSD95 Postsynaptic density protein95 突触后密度蛋白95 PVDF Polyvinylidene difiuoride 聚偏(二)氟乙烯 ROS Rosea 红景天 rpm Revolutions per minute 每分钟转速 RSV Resveratrol 白藜芦醇 Qrt-PCR QuantitativeRealfime- 实时荧光定量PCR PolymeraseChainReaction QUE Quercetin 槲皮素 SD Sprague Dawley 大鼠名称 SDS Sodium dodecyl sulfate 十二烷基硫酸钠 siRNA Small interfering RNA 小RNA干扰 SIRTl Sirtuin type l 沉默调节蛋白l SIRT3 Sirtuin type 3 沉默调节蛋白3 SYP Synaptophysin 突触素 2 万方数据 第三军医大学博士学位论文TBS 第三军医大学博士学位论文 TBS Tris-HCl buffered saline Tris．盐酸缓冲液 TBST Tris-HCl buffered saline+tween Tris．盐酸加吐温缓冲液 TEM Transmission electron microscopy 透射电子显微镜 TEMED N，N，N，N-tetramethyl—ethylene N,N,N,N-四甲基乙二胺 diamine TFAM Mitochondrial transcription factor A 1’ris Tris(hydroxyl methyl)aminomethane 三羟甲基氨基甲烷 Vdacl Voltage-dependent anion-selective 电压依赖性阴离子通道蛋白1 channel protein 1 uL Microliter 微升 uM Micromole 微摩尔 Ⅵ毋 Westem blot 蛋白免疫印迹 万方数据 第三军医大学博士学位论文The 第三军医大学博士学位论文 The protection of several polyphenolson on memory of rats under hypobaric hypoxia and the underying molecular mechanism Abstract Background and aims： On the plateau，air pressure and oxygen partial pressure decrease as altitude became higher and higher．Hypobalic hypoxia could have deleterious effects 0n cognitive functions， such as short-term memory，attention span and the ability of thinking and judgement of human beings and consequently harm normal life，working and studying．As the economy and society in plateau region develop，the cognitiv