急性脑梗死患者血栓弹力图的临床研究-康复医学与理疗学专业论文.docxVIP

万方数据 万方数据 目 录 中文摘要············································································································1 英文摘要····································································································4 英文缩写·······························································································7 研究论文 急性脑梗死患者血栓弹力图的临床研究 前言·························································································8 材料与方法······················································································9 结果······························································································12 附图································································································13 附表·······························································································15 讨论····································································································17 结论······································································································25 参考文献······························································································26 综述 血栓弹力图的临床应用··································································31 致谢··············································································································45 个人简历········································································································46 中 中 文 摘 要 PAGE 1万方数据 PAGE 1 万方数据 急性脑梗死患者血栓弹力图的临床研究 摘 要 目的：血栓弹力图（Thrombelastography，TEG）由德国Harlert于1948 年最早提出，是一种观察和研究血液凝固状态动态变化的辅助诊断手段， 对于血液的高凝或低凝状态是一种直观的较有价值的指标，属于血液流变 学检测的一种方法，早期仅用于进行试验研究，如今已经在指导临床成分 输血、监测及纠正高凝状态、救治创伤病人以及监测抗血小板药物疗效等 方面广为应用。TEG是对全血进行检测，它可以将凝血途径中纤维蛋白、 凝血因子等血浆成分以及血小板、红细胞等细胞组分对凝血的影响都涵盖 其中。作为当今严重危害人类身体健康的主要疾病之一，脑梗死致病原因 与多种因素相关。很多研究表明，脑血栓形成的主要机制是血小板激活及 凝血系统与纤溶系统之间的平衡发生紊乱。目前，对于脑血管病患者血栓 弹力图监测凝血状态相关报道较少，本试验则对急性脑梗死患者TEG结果 的变化及其各项参数与常规凝血指标之间的关联性进行了初步探讨。 方法：选取2014年12月—2015年11月在河北医科大学附属第二医院东 院区神经内科住院的122例急性脑梗死患者（均在发病