外科治疗缺血性心力衰竭(STICH)的研究概要.ppt 30页

Death or Cardiac Hospitalization  Kaplan-Meier Estimates of Primary Endpoint Death or Cardiac Hospitalization Kaplan-Meier Estimates of Primary Endpoint Mortality (All-Cause) Kaplan-Meier Estimates Mortality (All-Cause) Kaplan-Meier Estimates Summary of Outcomes in STICH H2 Hazard Ratios, Confidence Intervals, and Tests for Interaction 30-Day Mortality Outcome CABG N = 499 CABG + SVR N = 501 P Death Within 30 Days After Randomization All patients by intention to treat 22/499 (4.4%) 30/501 (6.0%) 0.26 Death During or Within 30 Days of Operation Operated patients by intention to treat 25/490 (5.1%) 26/489 (5.3%) 0.88 Operated patients by operation received 23/498 (4.6%) 28/481 (5.8%) 0.40 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0 1 2 3 4 5 Event Rate Years from Randomization CABG 499 501 319 319 270 275 220 216 99 11 23 23 CABG CABG+SVR No. at Risk 292 events 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0 1 2 3 4 5 Event Rate Years from Randomization CABG CABG+SVR HR 0.99 (95% CI: 0.84, 1.17), P=0.90 499 501 319 319 270 275 220 216 99 11 23 23 CABG CABG+SVR No. at Risk 292 events 289 events 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0 1 2 3 4 5 Mortality Rate Years from Randomization CABG 499 501 434 429 417 404 363 352 201 193 59 53 CABG CABG+SVR No. at Risk 141 deaths 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0 1 2 3 4 5 Mortality Rate Years from Randomization CABG+SVR HR 1.00 (95% CI: 0.79, 1.26), P=0.98 499 501 434 429 417 404 363 352 201 193 59 53 CABG CABG+SVR No. at Risk 141 deaths 138 deaths CABG 0.73 0.97 (0.80, 1.18) 204 (41%) 211 (42%) Hospitalization (cardiac) 0.96 1.01 (0.54, 1.87) 20 (4%) 22 (4%) Acute MI 0.35 0.77 (0.45, 1.32) 23 (5%) 31 (6%) Stroke 0.82 0.98 (0.83, 1.16) 268 (53%) 272 (55%) Hospitalization (all cause) 0.98 1.00 (0.79, 1.26) 138 (28%) 141 (28%) Death 0.90 0.99 (0.84, 1.17) 289 (58%) 292 (59%)