课件：ARDS与肺复张.ppt

肺泡复张的影响因素(3): 压力与时间 实现 open the lung and keep the lung open in the 24/26 pats Borges JB, …, Amato MBP. Am J Respir Crit Care Med Vol 174. pp 1–11, 2006 肺泡复张的影响因素(4):ARDS病程(早期　vs 后期) N=17 ARDS with a lung protective vent Early ARDS (n=9) vs Late ARDS (n=8, 7d) RM: PCV 2min at PIP 50cmH2O/PEEP PLIP Am J Respir Crit Care Med, 2002, 165:165–170 Paw [cmH2O] % Opening and Closing Pressures 0 5 10 15 20 25 30 35 40 45 50 0 10 20 30 40 50 Opening pressure Closing pressure 5 patients, ALI / ARDS From Crotti et al AJRCCM 2001. Some units can’t be kept open by any reasonable PEEP! 肺泡复