基于γ-氨基丁酸A型受体的鱼类受渔药影响的研究.doc

上海海洋大学博士学位论文 GABA-T也能产生影响，但二者所产生的影响难以对机体内GABA 含量变化加以 判断。 关键词：γ-氨基丁酸；γ-氨基丁酸A型受体；谷氨酸脱羧酶；GABA转氨酶；阿 维菌素；双氟沙星 IV 万方数据 上海海洋大学博士学位论文 The Research of Effects Caused by Fishery Drugs Based on Type A of Gamma-Aminobutyric Acid Receptor ABSTRACT Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter which mainly distributs in the central nervous system (CNS). In the body, GABA is synthesized from glutamate irreversibly and metabolized to succinic semialdehyde by glutamic acid decarboxylase (GAD) and GABA transaminase (GABA-T), respectively. And GAD has two isoforms, namely GAD65 and G