汕头大学医学院药理学精品课程 anti-angina.pptVIP

Antianginal drugs Angina pectoris is the severe chest pain that occurs when coronary blood flow is inadequate to supply the oxygen required by the heart. The primary cause of angina pectoris is an imbalance between the oxygen requirement of the heart and the oxygen supplied to it. Backgrounds of angina pectoris Classification: stable; unstable;variant Mechanism: Methods for treatment: To improve perfusion: To reduce metabolic demand Drugs organic nitrates; calcium antagonists β-Receptor blockers Organic nitrates Pharmacological effects and mechanism: dilate peripheral vein preload