运用腰池腹腔分流术与脑室腹腔分流术治疗交通性脑积液患者的Meta分析.docVIP

运用腰池-腹腔分流术与脑室-腹腔分流 术治疗交通性脑积液患者的Meta分析 吕东钟东张福安李炯黄浩洋杜伟夏海坚 重庆医科大学附属第一医院神经外科 摘要： 目的探讨脑室-腹腔(V-P)和腰池-腹腔(L-P)分流术治疗交通性脑积水患者 的疗效。方法采用计算机检索PubMcdx Web of Science、Scopuss、Kargcrx EBSCO+MEDLINE、OVID、EMBASE、中国知网、中国生物医学全文库、万方、维普 数据库，查出1990-2016年上述数据库所收录的有关L-P和V-P分流术治疗交通 性脑积液的相关文献，并运用STATA12. 0软件进行Meta分析。结果 交通性脑积 液患者予以L-P分流手术的成功率明显高于V-P分流术(P0. 05),术后感染 率、分流系统梗阻率及总并发症发生率较低(P0. 05),两组的分流欠佳率差异 无统计学意义(P0. 05)。结论L-P分流术在交通性脑积液患者中值得推荐， 由于证据质量较低，需要更多高质量的原始研究来弥补该研究的不足。 关键词： 交通性脑积液;腰池-腹腔分流术;脑室-腹腔分流术;Meta分析; 作者简介：吕东(1989-)，硕士，主要从事神经外科工作。 作者简介：钟东，E-nia订:zhongdongdp@sina. com。 收稿日期：2017-05-04 基金：国家临床重点专科建设项目(财社[2011]170号) Application of lumboperitoneal shunt and ventriculoperitoneal shunt in treatment of patients with communicating hydrocephalus:a Meta analysis Lyu Dong Zhong Dong Zhang Fuan Li Jiong Huang Haoyang Du Wei Xia Haijian Department of Neurosurgery, First Affiliated Hospital of Chongqing Medical University; Abstract： Objectivc To investigate the effect of lumboperitoneal (L-P) shunt and ventriculoperitoneal (V-P) shunt for treating the patients with communicating hydrocephalus. Methods The databases of PubMed, Web of Science, Scopuss, Karge, EBSCO+MEDLINE, OVID, EMBASE, CNKI, CBM disc databases, Wemfang databases, Wei pu databases were retrieved by computer. The rclcvant litcratures about L-P shunt and V-P shunt for treating communicating hydrocephalus included in these databases during 1990-2016 were collected and performed the meta analysis by using the STATA12. 0 software. Results The success rate of L-P shunt in treating communi cat ing hydrocephal us was appare ntly higher than that of VP shu nt (P0. 05) . Moreover, postoperative infcction rate, obstruction rate of shunt system and total postoperative complications rate in L-P shunt were apparently lower than those of V-P shunt (P〈0. 05) 、 However, there was no statistical difference in shunt poor rate between L-P shunt and V-P shunt (P0?05) . Conclusion I厂P shunt is worth recommending.But due to lower quality of the cvidcnccs，