根除幽门螺旋杆菌与不同亚型老年功能性消化不良疗效-现代仪器与医疗.PDFVIP

《现代仪器与医疗》 2017年  第23卷   第1期 临床研究 根除幽门螺旋杆菌与不同亚型老年功能性消化 不良疗效的关系 章悦　钟远 （上海市第六人民医院老年科，上海　200233 ） [摘　要]　目的：分析根除幽门螺旋杆菌（Helicobacter pylori ，HP ）与不同亚型老年功能性消化不良（Functional dyspepsia ，FD ）疗效的关系。方法：2013 年6 月—2015 年6 月收治184 例HP 阳性老年FD 患者，按照随机 数字表法分为抗HP 组、常规组各92 例。均予FD 常规治疗，抗HP 组加用HP 根除治疗，观察抗HP 组HP 根除成功情况，比较不同亚型患者治疗 1 个月后、治疗1 年后疗效及复发情况。结果：抗HP 组治疗1 个月 后、治疗 1 年后FD 治疗总有效率分别为78.26%、72.83% ，均高于常规组的59.78%、57.61% ；HP 根除成功组 治疗1 个月后、治疗1 年后总有效率分别为95.24%、98.21% ，均高于HP 根除失败组的68.42%、46.15% ；抗 HP 组EPS 亚型患者治疗1 个月后、治疗1 年后总有效率分别为86.00%、80.00%，均高于PDS 亚型的69.05%、 64.29% ，差异有统计学意义（ ＜0.05 ）。抗HP 组、常规组患者不良反应发生率分别为5.43%、6.52% ，组间 P 比较差异无统计学意义（ ＞0.05 ）。结论：根除HP 可提高EPS 型老年PD 患者临床疗效。 P [关键词]　幽门螺旋杆菌；老年；功能性消化不良；疗效 中图分类号：R573.6　文献标识码：A　文章编号：2095-5200(2017)01-077-03 DOI：10.11876/mimt201701031 Relationship between eradication of Helicobacter pylori and different subtypes of functional dyspepsia in elderly patients ZHANG Yue ZHONG Yuan. Department of Geriatrics,Shanghai No.6 People’s 　 ， （ Hospital,Shanghai 200233 China ） [Abstract]　Objective: This study objective was to analyze the relationship between eradication of Helicobacter pylori (HP) and different subtypes of functional dyspepsia (FD) in elderly patients. Methods: 184 elderly HP-positive FD patients admitted in our hospital from June 2013 to June 2015, were divided into anti-HP group and routine group (n=92) by the random number table. All patients were given conventional treatment of FD, anti-HP group was treated with HP eradication, and the eradication of HP in anti-HP group was observed, and the curative effect and recurrence of patients with different subtypes were compared between 1 month after treatment and 1 year after treatment. Results: The total effective rate of FD1 month after treatment and 1 year after treatment were 78.26% and 72.83%