淋巴结转移阴性大肠癌的临床病理特点及预后分析-肿瘤防治研究.PDFVIP

2·72 · 肿瘤防治研究 2008 年第 35 卷第 4 期 ·临床诊断 · 淋巴结转移阴性大肠癌的临床病理特点 及预后分析 高照华 Analysis of Cl inicopathologic Characteristics and Prognosis of Colorectal Cancer without Lymph Node Metastasis GAO Zhaohua D ep a rtment of Oncology , S heny ang R e d Cross H osp i t al , S heny ang 1100 13 , Chi na Abstract :Objective 　To investigat e t he clinicop at hologic feat ures of p atient s wit h no denegative met ast a si s (pN0) colorect al cancer confirmed by routine p at hologic examination ( H E st aining) ,and t heir rela tion ship wit h survival . Methods 　The clinicop at hologic dat a of 57 p N0 colorect al cancer p atient s were analyzed ret ro sp ectively . Kap lanMeier met hod wa s u sed to comp are t he survival rat e ,and Cox p ropor tional hazar d mo del was u sed to a ssess t he indep endent p ro gno si s factor s for pN0 colorect al cancer . Re sults 　Sero sa of mo st ca ses wa s not involved and t he p roportion of localized and welldifferentiat ed aden carcinoma was higher . The 5year survival rat e wa s 83 . 1 %. Conclusion 　Patient s wit h colorect al cancer wit hout lymp h node met a st a si s may have well p rogno si s since radical resection wa s p erformed . Invasive dep t h was t he indep endent p rogno stic factor . Key words :Colorect al cancer ;L ymp h no de met a st a si s ;Radical resection ; Progno si s ( ) 摘 　要 : 目的 　探讨常规病理检查淋巴结转移阴性 p N0 大肠癌患者的预后因素 。方法 　回顾性分析 57 例 p N0 大肠癌患者的临床病理特点及其与预后的关系 。结果 　淋巴结转移阴性大肠癌浸润深度较 浅 、很少浸透浆膜 ,限局型 、高分化腺癌较多 ;术后 5 年生存率为83 . 1 % 。结论 　淋巴结转移阴性大肠癌 施行根治术后预后较好 ,浸润深度和大体类型是其独立预后因素 。 关键词 :大肠癌 ;淋巴结转移 ;根治术 ;预后 中图分类号 :R735 . 3 + 4 　　文献标识码 :A 　　文章编号 (2008) ( ) (