影响踝臂脉搏波传导速度的危险因素及相关研究.docVIP

影响踝?臂脉搏波传导速度的危险因素及相关研究 新疆医科大学第一附属医院高血压科新疆乌鲁木齐830054 摘 要 目的分析影响踝■臂脉搏波传导速度（baPWV）的因素及baPWV与 冠心病、高血压、脑梗塞等疾病患病率的相关性。方法随机抽取2007年1月 至2009年10月新疆医科大学第一附属医院高血压科病历资料完整的住院患者 104例。使用日木Colin公司生产的动脉僵硬度早期检测仪VP-100进行踝臂脉搏 波速度检测，收集患者的年龄、性别、血脂、颈部血管超声、头颅CT/MRL冠 脉造影等临床资料。按baPWV值将研究对象分为baPWV14m/s组和 baPWVge;14m/s组，以踝臂脉搏波速度ge;14m/s组作为动脉僵硬度增高的诊 断标准。结果年龄、收缩压（SBP）、舒张压（DBP）、心率、低密度脂蛋白、 总胆固醇在两组间比较中具有统计学差异（PV0.05）；性别、高密度脂蛋白、甘 油三酯在两组间无统计学差异（P0.05）。二元logistic回归显示年龄（PV0.05, OR 0.898, 95%CI 0.814?0.991）,收缩压（PV0.05, OR 0.871, 95% Cl 0.781 ? 0.972）,总胆固醇（P0.05, OR 1.011, 95%CI 0.937?1.132）,低密度脂蛋 白（PV0.05, OR 0.936, 95%CI 0.811~0.978）。冠心病、脑梗塞、颈部血管 病变的发牛率在两组间有统计学差异（P0.05）o结论年龄、收缩压（SBP）、 舒张压（DBP）、心率、总胆固醇、低密度脂蛋白为baPWV的危险因素，其中以 年龄、收缩压（SBP）、总胆固醇、低密度脂蛋白最为明显。冠心病、脑梗塞、颈 部血管病变的发牛率在baPWVge;14m/s组要高于baPWV14m/s组baPWV可 作为评价心脑血管弹性改变的指标之一。 关键词 动脉僵硬度；踝臂脉搏波传导速度；高血压；冠心病；脑梗塞。 The Factors for Ankle-brachial Pulse Wave Velocity and Some Relative Research Liu Haiming, Zhang Junshi, Xu Xinjuan Abstract Objective To study the risk for ankle-brachial pulse wave velocity（baPWV） and the associativity with baPWV and some clinical disease like coronary atherosclerotic heart disease et. Methods To test the baPWV from the patient who were in the Hypertension apartment of Xin Jiang Medical University by arterial stiffness early detection equipment VP-100 made in Colin company of Japan. Collected the age, gender and some other clinical data. Divided subjects into baPWV 14m/s group and baPWVge;14m/s group, and to consider baPWVge;14m/s as the arterial stiffness in creased. Results Compared baPWV14m/s group with baPWVge;14m/s group, age, SBP, heart rate and some other gen era I data exsited statistic sign讦icance (P0?05), gender, HDL and some other clinical data didnrsquo;t exsited statistic significance (P0.05) ? Binary lofistic regression showed that age (P0.05, OR 0.898, 95%CI 0.814^0.991), SBP (P0.05, OR 0.898, 95%CI 0.814^0.991), TC(P0.05, OR 1.011, 95%CI 0.937^1.132), LDL (P0.05, OR 0.936, 95%CI 0.811^0.978)? Conclusions Age, SBP, T