探讨妊娠前体重指数和胎次对妊娠糖尿病合并甲状腺功能减退症发病的影响.docVIP

探讨妊娠前体重指数和胎次对妊娠糖尿病合并甲状腺功能减退症发病的影响 五常市小山子镇卫生院150211 摘 要 目的研究分析妊娠前体重指数和胎次对妊娠糖尿病合并甲状腺功能 减退症发病的影响。方法 此次研究的对彖是选择2014年8月?2015年12月就 诊我院的150例妊娠期妇女，将其临床资料进行回顾性分析，并先按照患者妊娠 前的体重指数（BMI）将患者分为体重正常组（52例）、肥胖前期组（47例）以 及肥胖组（51例），再按照胎次数将患者分为单胎组（70例）和多胎组（80例）。 分别检测记录各组患者的血清游离三碘甲状腺原氨酸（FT3）、血清游离甲状腺素 （FT4）和促甲状腺激素（TSH）的水平；统计比较各组妊娠糖尿病合并甲减的发 病率；采用非条件Logistic回归模型分析妊娠糖冰病合并甲减的影响因素。结果 肥胖前期组和肥胖组患者血清FT3、FT4的水平较体重正常组明显降低，而TSH 的水平明显升高，差异均有统计学意义（PIt; 0.05）；体重正常组、肥胖前期组 以及肥胖组患者的妊娠糖尿病合并甲减发病率分别为1.9%. 3.5%和10.0%,肥胖 前期组和肥胖组与体重正常组比较，妊娠糖尿病合并甲减发病率明显升高，差异 有统计学意义（PIt; 0.05）；单胎组和多胎组患者的妊娠糖尿病合并甲减发病率 分别为1.5%和12.0%,多胎组与单胎组比较，妊娠糖尿病合并甲减发病率有明显 的升高，差异有统计学意义（P It; 0.05）；非条件Logistic回归分析发现，胎次 和BMI都是妊娠糖尿病合并甲减的重要影响因素（回归系数分别为0.854.0.698）o 结论妊娠前BMI和胎次对妊娠糖丿求病合并甲减发病的影响重大，有很高的评估 价值。 关键词 妊娠前；体重指数；胎次；妊娠糖尿病合并甲减；影响 [Abstract] Objective To analyze the pregnancy body mass index before and parity on gestational diabetes mellitus complicated with thyroid dysfunction diseases. Methods the study object is 2014 August to December 2015 treatment in our hospital of 150 cases of pregnant women, their clinical data were retrospectively analyzed, and in accordance with the pre pregnancy body mass index (BMI) the patients were divided into the normal weight group (52 cases), pre obese group (47 cases)and obesity group(51 cases), then in accordanee with the number of fetal will patients were divided into single pregnancy group (70 cases) and multiple pregnancy group (80 cases) . Were used to detect the records in each group of patients with serum free three iodine thyroid original ammonia acid (FT3)，free thyroxine (FT4) and promote thyroid hormone (TSH) levels. Statistical comparison of each pregnancy incidence of diabetes complicated with hypothyroidism ； using non conditional logistic regressi on model to an a lyze the in flue ntial factors on the preg nancy diabetes complicated with hypothyroidism. The pre obese group and obese group serum FT3 and FT4 levels compared with normal weight group significantly decreased, while the level of TSH in