氨基酸的分解及其与葡萄糖交互作用机理研究.docxVIP

基金项目：中国博士后基金特别资助（2017T100553） 通信作者：陈应泉，博士后，主要从事生物质热解多联产与生物质碳基材料和催化剂研究，E-mail: chenyingquan@ 中国工程热物理学会 燃烧学 学术会议论文 编号：184187 氨基酸的分解及其与葡萄糖交互作用机理研究 宫梦1，方阳1，陈伟1，杨海平1, 陈应泉1，陆强3，陈汉平1，2 （1. 华中科技大学，能源与动力工程学院，煤燃烧国家重点实验室，武汉 430074； 2. 华中科技大学，能源与动力工程学院，新能源科学与工程系，武汉 430074； 3. 华北电力大学,可再生能源学院,生物质发电成套设备国家工程实验室,北京 102206） (Tel: Email: gongmemg312@126.com) 摘 要 本文通过Py-GC/MS将苯丙氨酸和谷氨酸分别与葡萄糖共热解，得出交互作用机理：苯丙氨酸和谷氨酸抑制葡萄糖开环向呋喃类产物转化及脱水形成左旋葡聚糖。谷氨酸促进5-羟甲基糠醛分解成5-甲基糠醛。葡萄糖抑制苯丙氨酸脱羧产生苯乙胺，促进L-焦谷氨酸脱羧形成2-吡咯烷酮。采用密度泛函理论，在B3LYP/6-31++G(d,p)水平上对氨基酸分解进行计算。结果表明苯丙氨酸能垒较低的路径是分子间脱水形成二肽，谷氨酸是分子内脱水生成L-焦谷氨酸，与实验结果基本一致。 关键词 苯丙氨酸；谷氨酸；葡萄糖；密度泛函理论；Py-GC/MS Decomposition of Amino Acids and Mechanism of Interaction with Glucose Gong Meng1, Fang Yang1, Chen Wei1, Yang Haiping1, Chen Yingquan1, Lu Qiang3, Chen Hanping1,2 (1. State Key Laboratory of Coal Combustion, Huazhong University of Science and Technology, Wuhan 430074, China; 2. China-EU Institute for Clean and Renewable Energy, Huazhong University of Science and Technology, Wuhan 430074, China; 3. National Engineering Laboratory for Biomass Power Generation Equipment, North China Electric Power University, Beijing 102206, China) (Tel: Email: gongmemg312@126.com) Abstract Analysising of co-pyrolysis of phenylalanine and glutamic acid mixed with glucose respectively by Py-GC/MS, it was obtained the interaction mechanism: phenylalanine and glutamic acid not only inhibited the conversion of furan products by ring-opening of glucose, but also inhibited the forming of levoglucosan by dehydration. Glutamic acid promoted the decomposition of 5-hydroxymethylfurfural to 5-methylfurfural. Glucose inhibited the formation of phenylethylamine by decarboxylation of phenylalanine and promoted decarboxylation of L-pyroglutamic acid to 2-pyrrolidone. The pyrolysis pathways of amino acids was investigated by using density function