临床上联合用药治疗结核病的效果分析.docxVIP

临床上联合用药治疗结核病的效果分析 湖南省胸科医院湖南长沙410006 【摘 要】目的探究临床上联合用药治疗结核病的效果。方法选取我院在2013 年10月至2015年10月的结核病患者148例进行治疗，随机分成对照组和实验 组，每组74例患者对照组采用异烟月井、利福平、毗嗪酰胺治疗，实验组使用异 烟月井、利福平、左氧氟沙星共同治疗。结果实验组结果显示，痊愈33例，有效 38例，无效3例，总有效率为95.9%o对照组痊愈18例，有效36例，无效20 例，治疗总有效率为73.0%,实验组效果明显好于对照组。实验组患者的治疗总 有效率显著高于对照组患者，?且Plt;0.05,差异具有统计学意义。实验组出现胃 肠道症状9例，肝功能损害，7例，白细胞减少3例，不良反应率为25.7%。对 照组的胃肠道症状12例，肝功能损害15例，白细胞减少10例，不良反应率为 50%。实验组的不良反应率明显低于对照组。结论将非传统抗结核药物左氧氟沙 星用于抗结核治疗，其治疗效果良好，且药物不良反应较少，可考虑用于对毗嗪 酰胺耐受程度低的患者替代治疗，值得在临床应用中推广。 【关键词】联合用药；结核病；左氧氟沙星 [Abstract]Objective: To explore the clinical effect of combined drug treatment on tuberculosis. Methods in our hospital in October October 2013 to 2015 of TB patients in 148 cases were treated randomly divided into experimental group and control group, each group 74 cases of patients in control group were treated with isoniazid, r讦ampicin, pyrazinamide, the experimental group use of isoniazid, rifampicin, levofloxacin in treatment of. Results the experimental group showed that 33 cases were cured, 38 cases were effective, 3 cases were ineffective, the total effective rate was 95.9% .In the control group, 18 cases were cured, 36 cases were effective, 20 cases were in effective, the total effective rate was 73%, the experime ntal group was significantly better than the control group. The total effective rate of the experimental group was significantly higher than that of the control group, and Plt;0.05, the d iff ere nee was statistically significant. In the experimental group, there were 9 cases of gastrointestinal symptoms, liver function damage, 7 cases, and 3 cases of white blood cells, the adverse reaction rate was 25.7%. The control group of 12 cases of gastrointestinal symptoms, liver function damage in 15 cases, 10 cases of white blood cells, adverse reaction rate was 50%. The adverse reaction rate of the experimental group was significantly lower than that of the control group. Conclusion the non traditional anti tuberculosis drug levofloxacin for anti tuberculosis th