唑来膦酸联合PKPPVP治疗老年骨质疏松性椎体骨折的临床疗效.docxVIP

呼来麟酸联合PKPPVP治疗老年骨质疏松性椎体骨折的临床 疗效 李庆富 张胡 李保健 张闻生 扈桂海 (山东省聊城市第二人民医院骨科 山东聊城252600) 【摘要】FI的：研究分析卩坐來麟酸联合PKP/PVP治疗老年骨质疏松性椎体骨 折的临床疗效。方法：随机选取聊城市第二人民医院骨科2013年12月至2015 年08月住院治疗的骨质疏松性椎体骨折60例作为研究对象，分为2组，每组各 30例，分别为单纯PKP/PVP治疗的对照组和PKP/PVP联合呼来麟酸治疗的实验 组，比较2组患者在治疗前和治疗后3月、6月进行股骨近端骨密度测量，疼痛 VAS临床评分的差异，评价治疗效果。结果：经统计分析得出，实验组患者股骨 近端骨密度明显提高，脊柱骨疼痛症状较对照组得到持续缓解，治疗后半年内无 新发骨折。对照组半年期间有脊柱骨性疼痛加重趋势，5例患者术后半年内再次 出现新发椎体骨质疏松性骨折。结论：经研究得出，在对骨质疏松性椎体骨折患 者的治疗方面，呼来麟酸联合骨水泥技术治疗老年骨质疏松性骨折效果显著，可 明显提高骨质疏松性患者骨密度，有效减轻全身及胸腰部骨性疼痛症状，降低再 次骨折发生率，提高患者生活质量，可作为骨质疏松性骨折的良好治疗措施。 【关键词】卩坐來麟酸；骨质疏松；性椎体骨折 【中图分类号】R68 【文献标识码】A 【文章编号】1007-8231 (2016) 05-0048-02 [Abstract] Objective To study the clin ical effect of the treatme nt of se nile osteoporotic vertebral fracture with the combi nation of PKP/PVP and P. 60 cases as the research object, is divided into two groups, each with 30 cases in each, respectively simple PKP/PVP treatment control group and PKP/PVP combined with zoledronic acid therapy in the experimental group, compared two groups of patients before treatme nt and after treatme nt in 3 mon ths, 6 mon ths of femoral bone den sity measureme nts of the proximal, the d iff ere nee of cli nical pain VAS score, to evaluate the therapeutic effect Methods Randomly selected from Department of Orthopaedics, the second peoples Hospital of Liaocheng City August December 2013 to 2015 for inpatient treatment of osteoporotic vertebral fracture. Results Through statistical analysis, the experimental group of patients with proximal femoral bone mineral den sity in creased sign ifica ntly, the spinal bon e pain symptoms tha n the control group was sustained remission, no new hair fractures within six months after treatment. In the control group, there was a trend of spinal bone pain during half a year, 5 cases of patients with new vertebral osteoporotic fractures occurred in the second half of the year. Conclusion The study con eluded that, in osteoporotic vertebral fracture patients with the treatment of azole to phosphonic acid combined