四神丸联合复方嗜酸乳杆菌片治疗慢性腹泻疗效观察.PDFVIP

现代药物与临床 Drugs Clinic 第 33 卷 第 9 期 2018 年 9 月 ·2369 · 四神丸联合复方嗜酸乳杆菌片治疗慢性腹泻的疗效观察 歧红阳，王云溪，董志超，吴凤丽 新乡市中心医院 消化内科，河南 新乡 453000 摘 要：目的 探究四神丸联合复方嗜酸乳杆菌片治疗慢性腹泻的临床疗效。方法 选取 2015 年 6 月—2017 年 3 月新乡市 中心医院收治的 174 例慢性腹泻患者为研究对象，采取随机双盲法将患者分为对照组和治疗组，每组各 87 例。对照组口服 复方嗜酸乳杆菌片，0.5～2 片/次，3 次/d 。治疗组患者在对照组治疗的基础上口服四神丸，0.5～1 袋/次，1～2 次/d 。两组 患者均连续治疗 5 d 。观察两组患者临床疗效，比较两组患者的临床症状改善时间。结果 治疗后，对照组和治疗组的总有 效率分别为 78.16%、97.70%，两组比较差异具有统计学意义（P ＜0.05 ）。治疗后，治疗组患者排便次数、粪便性状、腹痛、 食欲不振、倦怠乏力改善时间均短于对照组，两组比较差异具有统计学意义（P ＜0.05 ）。结论 四神丸联合复方嗜酸乳杆菌 片治疗慢性腹泻效果显著，可明显改善症状，安全可行，具有一定的临床推广价值。 关键词：四神丸；复方嗜酸乳杆菌片；慢性腹泻；临床症状改善时间 中图分类号：R975 文献标志码：A 文章编号：1674 - 5515(2018)09 - 2369 - 03 DOI: 10.7501/j.issn.1674-5515.2018.09.047 Clinical observation of Sishen Pills combined with Compound Eosinophil-Lactobacillus Tablets in treatment of chronic diarrhea QI Hong-yang, WANG Yun-xi, DONG Zhi-chao, WU Feng-li Department of Gastroenterology, Xinxiang Central Hospital, Xinxiang 453000, China Abstract: Objective To investigate the clinical efficacy of Sishen Pills combined with Compound Eosinophil-Lactobacillus Tablets in treatment of chronic diarrhea. Methods Patients (174 cases) with chronic diarrhea in Xinxiang Central Hospital from June 2015 to March 2017 were randomly divided into control group and treatment groups according to double-blind, and each group had 87 cases. Patients in the control group were po administered with Compound Eosinophil-Lactobacillus Tablets, 0.5 — 2 tablets/ time, three times daily. Patients in the treatment group were po administered with Sishen Pills on the basis of the control group, 0.5 — 1 bag/time, 1 — 2 times/d. Patients in two groups were treated for 5 d. After treatment, the clinical efficacies were evaluated, and the improvement times of clinical symptoms in two groups were compared.