中性粒细胞趋化因子在轻重症急性胰腺炎大鼠胰腺组织中-江苏大学.PDF

20 5 ( ) Vol. 20 No. 5 2010 9 Journal of Jiangsu University(M edicine Edition) Se t. 2010 1 1 2 2 2 2 2 2 徐 萍, 徐 岷 , 周国雄, 黄介飞, 张 弘, 魏 群 , 江 枫, 肖明兵 ( 1. , 212001; 2. , 226001) [ ] : ( cytok ineinduced neutro h il chem oattractant, CINC) (m ild acu te ancreatitis, MAP)( severe acute ancreatitis, SAP): 5% SD ( 18)( 18) ( 24) ( 24), , - ( RTPCR ) C INC C INC mRNA : 6, 12 h C INC C INC mRNA (P 0. 05), ; 24 h , ; 1 h C INC C INC mRNA , (P 0. 05, P 0. 01): C INC MAP SAP [] ; ; [] R576 [] A [] 1671- 7783( 2010) 05- 0377- 05 Expression of cytokineinduced neutrophil chemoattractant inmild or severe acute pancreatitis rats 1 1 2 2 2 X U P ing , X U M in , ZH OU G uox iong , H UANG J iefei , ZHAN G H ong , 2 2 2 WE I Qun , JIAN G F eng , X IA O M ing bing ( 1. De artm ent of Endocrinology, the A ffiliatedH os ital of Jiangsu University, Zhenjiang Jiangsu 212001; 2. De artm ent ofGastroenterology, theA ffiliated Hos ital of Nantong U niversity, N antong Jiangsu 226001, China) [Abstract] Objective: To investigate the role of cytokineinduced neutro h il chemoattractant( CINC) in the course of exchange from m ild acute ancreatitis(MAP) to severe acute ancreatitis( SAP). Methods: Acute ancreatitis model w as induced by intra eritoneal injection of cerulein or retrograde infusion of 5% sod ium